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  1. Article

    Open Access

    The desirability of education in didactic skills according to medical interns

    Since all doctors at some point in their career will be faced with their role as a teacher, it appears desirable that future doctors are educated in didactic skills. At present, however, there are no formal op...

    Anne T. Kloek, Joshua R. A. Verbakel in Perspectives on Medical Education (2012)

  2. Article

    Open Access

    Exome Array Analysis of Susceptibility to Pneumococcal Meningitis

    Host genetic variability may contribute to susceptibility of bacterial meningitis, but which genes contribute to the susceptibility to this complex disease remains undefined. We performed a genetic association...

    Anne T. Kloek, Jessica van Setten, Arie van der Ende, Michiel L. Bots in Scientific Reports (2016)

  3. Article

    Open Access

    How a teaching rotation in medical school affects graduates’ subsequent careers

    Teaching opportunities and teacher courses for medical students are increasingly offered by medical schools but little has been investigated about their long-term effect. The aim of our study was to investigat...

    Anne T. Kloek, Angela C.M. van Zijl in Perspectives on Medical Education (2016)

  4. Article

    Open Access

    Host genetic variability and pneumococcal disease: a systematic review and meta-analysis

    Pneumonia, sepsis, meningitis, and empyema due to Streptococcus pneumoniae is a major cause of morbidity and mortality. We provide a systemic overview of genetic variants associated with susceptibility, phenotype...

    Anne T. Kloek, Matthijs C. Brouwer, Diederik van de Beek in BMC Medical Genomics (2019)

  5. Article

    Open Access

    Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage

    Previous studies showed that complement activation is associated with poor functional outcome after aneurysmal subarachnoid hemorrhage (SAH). We investigated whether complement activation is underlying brain i...

    Bart J. van Dijk, Joost C.M. Meijers, Anne T. Kloek in Translational Stroke Research (2020)

  6. Article

    Open Access

    Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

    Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles ha...

    Anne T. Kloek, Mercedes Valls Seron, Ben Schmand in Acta Neuropathologica Communications (2021)