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Article
Open AccessIndividual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis
Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles ha...
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Article
Open AccessComplement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage
Previous studies showed that complement activation is associated with poor functional outcome after aneurysmal subarachnoid hemorrhage (SAH). We investigated whether complement activation is underlying brain i...
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Article
Open AccessHost genetic variability and pneumococcal disease: a systematic review and meta-analysis
Pneumonia, sepsis, meningitis, and empyema due to Streptococcus pneumoniae is a major cause of morbidity and mortality. We provide a systemic overview of genetic variants associated with susceptibility, phenotype...
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Article
Open AccessHow a teaching rotation in medical school affects graduates’ subsequent careers
Teaching opportunities and teacher courses for medical students are increasingly offered by medical schools but little has been investigated about their long-term effect. The aim of our study was to investigat...
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Article
Open AccessExome Array Analysis of Susceptibility to Pneumococcal Meningitis
Host genetic variability may contribute to susceptibility of bacterial meningitis, but which genes contribute to the susceptibility to this complex disease remains undefined. We performed a genetic association...
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Article
Open AccessThe desirability of education in didactic skills according to medical interns
Since all doctors at some point in their career will be faced with their role as a teacher, it appears desirable that future doctors are educated in didactic skills. At present, however, there are no formal op...