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Article
Open AccessIncidence and risk factors of hepatocellular carcinoma in patients with hepatitis C in China and the United States
Hepatitis C virus (HCV) infection is the main cause of hepatocellular carcinoma (HCC) in the United States (US) and an increasingly common cause of HCC in China. We aimed to evaluate the incidence and risk fac...
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Article
Open AccessBiliary NIK promotes ductular reaction and liver injury and fibrosis in mice
Excessive cholangiocyte expansion (ductular reaction) promotes liver disease progression, but the underlying mechanism is poorly understood. Here we identify biliary NF-κB-inducing kinase (NIK) as a pivotal re...
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Article
Open AccessImplementation of a randomized mobile-technology lifestyle program in individuals with nonalcoholic fatty liver disease
Identifying effective, feasible, low-cost interventions that promote sustainable lifestyle changes in nonalcoholic fatty liver disease (NAFLD) is a key unmet need. The aim of this study was to assess predictor...