4 Result(s)

Article

Dual anti-HER2/EGFR inhibition synergistically increases therapeutic effects and alters tumor oxygenation in HNSCC

Epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and hypoxia are associated with radioresistance. The goal of this study is to study the synergy of anti-HER2, trastuzum...

Patrick N. Song, Shannon E. Lynch, Chloe T. DeMellier, Ameer Mansur… in Scientific Reports (2024)

Article

Author Correction: Positron emission tomography imaging with ⁸⁹Zr-labeled anti-CD8 cys-diabody reveals CD8⁺ cell infiltration during oncolytic virus therapy in a glioma murine model

Benjamin B. Kasten, Hailey A. Houson, Jennifer M. Coleman… in Scientific Reports (2021)

Article

Positron emission tomography imaging with ⁸⁹Zr-labeled anti-CD8 cys-diabody reveals CD8⁺ cell infiltration during oncolytic virus therapy in a glioma murine model

Determination of treatment response to immunotherapy in glioblastoma multiforme (GBM) is a process which can take months. Detection of CD8⁺ T cell recruitment to the tumor with a noninvasive imaging modality such...

Benjamin B. Kasten, Hailey A. Houson, Jennifer M. Coleman… in Scientific Reports (2021)

Article

Experimentally-driven mathematical modeling to improve combination targeted and cytotoxic therapy for HER2+ breast cancer

The goal of this study is to experimentally and computationally investigate combination trastuzumab-paclitaxel therapies and identify potential synergistic effects due to sequencing of the therapies with in vitro

Angela M. Jarrett, Alay Shah, Meghan J. Bloom, Matthew T. McKenna… in Scientific Reports (2019)