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  1. Article

    Open Access

    Sex-specific differences in myocardial glucose metabolic rate in non-diabetic, pre-diabetic and type 2 diabetic subjects

    Evidence has shown that women with type 2 diabetes (T2DM) have a higher excess risk for cardiovascular disease (CVD) than men with T2DM. Subjects with either T2DM or prediabetes exhibit myocardial insulin resi...

    Elena Succurro, Patrizia Vizza, Francesco Cicone in Cardiovascular Diabetology (2024)

  2. Article

    Open Access

    Mean platelet volume (MPV) as new marker of diabetic macrovascular complications in patients with different glucose homeostasis

    Platelets play an important role in the development of cardiovascular disease (CVD). Mean platelet volume (MPV) is considered as biological marker of platelets activity and function. The aim of the present stu...

    Velia Cassano, Giuseppe Armentaro, Domenico Iembo in Cardiovascular Diabetology (2024)

  3. Article

    Open Access

    Sex-related differences for uric acid in the prediction of cardiovascular events in essential hypertension. A population prospective study

    Uric acid (UA) is an independent prognostic factor for cardiovascular events, but there are no data demonstrating a different risk profile between women and men. Thus, we tested whether UA is associated with a...

    Maria Perticone, Raffaele Maio, Ermal Shehaj in Cardiovascular Diabetology (2023)

  4. Article

    Open Access

    Impaired insulin-stimulated myocardial glucose metabolic rate is associated with reduced estimated myocardial energetic efficiency in subjects with different degrees of glucose tolerance

    Alterations in myocardial mechano-energetic efficiency (MEEi), which represents the capability of the left ventricles to convert the chemical energy obtained by oxidative metabolism into mechanical work, have ...

    Elena Succurro, Francesco Cicone, Annalisa Papa, Sofia Miceli in Cardiovascular Diabetology (2023)

  5. Article

    Open Access

    Progressive right ventricular dysfunction and exercise impairment in patients with heart failure and diabetes mellitus: insights from the T.O.S.CA. Registry

    Findings from the T.O.S.CA. Registry recently reported that patients with concomitant chronic heart failure (CHF) and impairment of insulin axis (either insulin resistance—IR or diabetes mellitus—T2D) display ...

    Andrea Salzano, Roberta D’Assante, Massimo Iacoviello in Cardiovascular Diabetology (2022)

  6. Article

    Open Access

    The TRIB3 R84 variant is associated with increased left ventricular mass in a sample of 2426 White individuals

    Prior studies in animal models showed that increased cardiac expression of TRIB3 has a pathogenic role in inducing left ventricular mass (LVM). Whether alterations in TRIB3 expression or function have a pathog...

    Gaia Chiara Mannino, Carolina Averta in Cardiovascular Diabetology (2021)

  7. Article

    Open Access

    Sex-specific differences in left ventricular mass and myocardial energetic efficiency in non-diabetic, pre-diabetic and newly diagnosed type 2 diabetic subjects

    Women with type 2 diabetes (T2DM) have a higher excess risk for cardiovascular disease (CVD) than their male counterparts. However, whether the risk for CVD is higher in prediabetic women than men is still deb...

    Elena Succurro, Sofia Miceli, Teresa Vanessa Fiorentino in Cardiovascular Diabetology (2021)

  8. Article

    Open Access

    Ferritin modifies the relationship between inflammation and arterial stiffness in hypertensive patients with different glucose tolerance

    Ferritin, a crucial element for iron homeostasis, is associated with chronic diseases characterized by subclinical inflammation such as essential arterial hypertension and type 2 diabetes mellitus (T2DM), show...

    Angela Sciacqua, Ettore Ventura, Giovanni Tripepi in Cardiovascular Diabetology (2020)

  9. Article

    Open Access

    Vitamin D and 1-hour post-load plasma glucose in hypertensive patients

    A plasma glucose value ≥155 mg/dl for 1-hour post-load plasma glucose during an oral glucose tolerance test (OGTT) is able to identify subjects with normal glucose tolerance (NGT) at high-risk for type-2 diabe...

    Angela Sciacqua, Maria Perticone, Nadia Grillo, Tania Falbo in Cardiovascular Diabetology (2014)