-
Article
Open AccessSDPR expression in human trabecular meshwork and its potential role in racial disparities of glaucoma
In order to identify how differential gene expression in the trabecular meshwork (TM) contributes to racial disparities of caveolar protein expression, TM dysfunction and development of primary open angle glau...
-
Reference Work Entry In depth
Corneal Wound Healing, Recurrent Corneal Erosions, and Persistent Epithelial Defects
The process of corneal wound healing involves tightly regulated epithelial proliferation, differentiation, migration, and matrix remodeling. When the corneal epithelium fails to regenerate and adhere to the un...
-
Living Reference Work Entry In depth
Corneal Wound Healing, Recurrent Corneal Erosions, and Persistent Epithelial Defects
The process of corneal wound healing involves tightly regulated epithelial proliferation, differentiation, migration, and matrix remodeling. When the corneal epithelium fails to regenerate and adhere to the un...
-
Chapter
Posterior Blepharitis
Posterior blepharitis is a common, chronic inflammatory condition that includes meibomian gland dysfunction (MGD). It is associated with sex hormones, older age, rosacea, many other systemic conditions, isotre...
-
Article
Open AccessTRPV1 activity and substance P release are required for corneal cold nociception
As a protective mechanism, the cornea is sensitive to noxious stimuli. Here, we show that in mice, a high proportion of corneal TRPM8+ cold-sensing fibers express the heat-sensitive TRPV1 channel. Despite its ins...
-
Article
Anatomical and functional dichotomy of ocular itch and pain
Itch and pain are refractory symptoms of many ocular conditions. Ocular itch is generated mainly in the conjunctiva and is absent from the cornea. In contrast, most ocular pain arises from the cornea. However,...
-
Article
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
Kathy Sivils and colleagues report results of a large-scale association study of Sjögren's syndrome, a common autoimmune disease. They confirm strong associations with the HLA region and establish genome-wide ...
-
Chapter
Co-Expression of BCL-2 and CD44S in Basal Layers of Human Ocular Surface Epithelia
The regulating mechanism of life and death of cells is a closely coordinated process of adaptation and survival. Selective and controlled cell death is a dominant force in renewing the tissue composition of co...
