10 Result(s)
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Article
Open AccessHyaluronidase inhibitor delphinidin inhibits cancer metastasis
Cancer remains a formidable global health challenge, with metastasis being a key contributor to its lethality. Abundant high molecular mass hyaluronic acid, a major non-protein component of extracellular matri...
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Article
Open AccessInvariant γδTCR natural killer-like effector T cells in the naked mole-rat
The naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing resistance to the development of cancer. Although naked mole-rats have been reported to lack natural killer (NK) cells, γδ T cell-...
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Article
Open AccessEvolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle
Hyaluronic acid is a major component of extracellular matrix which plays an important role in development, cellular response to injury and inflammation, cell migration, and cancer. The naked mole-rat (Heterocepha...
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Article
Open AccessIntegration of fluorescence in situ hybridization and chromosome-length genome assemblies revealed synteny map for guinea pig, naked mole-rat, and human
Descriptions of karyotypes of many animal species are currently available. In addition, there has been a significant increase in the number of sequenced genomes and an ever-improving quality of genome assembly...
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Open AccessEpigenetic aging of the demographically non-aging naked mole-rat
The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of mortality with age, defining it as a demographically non-aging mammal. Here, we perform bisulfite sequencing of the bloo...
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Open AccessNaked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if exceptional polymer length of vHMM-HA is ...
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Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessPublisher Correction: Lipidome determinants of maximal lifespan in mammals
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessLipidome determinants of maximal lifespan in mammals
Maximal lifespan of mammalian species, even if closely related, may differ more than 10-fold, however the nature of the mechanisms that determine this variability is unresolved. Here, we assess the relationshi...
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Article
Correction: Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax
Nature Communications 5: Article number: 3966 (2014); Published online: 3 June 2014; Updated: 12 Aug 2015. In Fig. 2 of this Article, the CLOCK protein sequence of the blind mole rat (Spalax) was inadvertently...
