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  1. Article

    Open Access

    OncoScape: Exploring the cancer aberration landscape by genomic data fusion

    Although large-scale efforts for molecular profiling of cancer samples provide multiple data types for many samples, most approaches for finding candidate cancer genes rely on somatic mutations and DNA copy nu...

    Andreas Schlicker, Magali Michaut, Rubayte Rahman in Scientific Reports (2016)

  2. Article

    Open Access

    Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer

    Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular...

    Magali Michaut, Suet-Feung Chin, Ian Majewski, Tesa M. Severson in Scientific Reports (2016)

  3. No Access

    Article

    Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

    Patients with melanomas carrying an activating BRAF mutation respond to treatment with BRAF inhibitors although resistance to the inhibitor usually emerges; this resistance is shown to arise through increased exp...

    Chong Sun, Liqin Wang, Sidong Huang, Guus J. J. E. Heynen, Anirudh Prahallad in Nature (2014)