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Article
Open AccessGenetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2
DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both have demonstrated roles in neuronal migration, in cilia growth and function and they both are cytosk...
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Article
Open AccessDyslexia Candidate Gene and Ciliary Gene Expression Dynamics During Human Neuronal Differentiation
Developmental dyslexia (DD) is a neurodevelopmental condition with complex genetic mechanisms. A number of candidate genes have been identified, some of which are linked to neuronal development and migration a...
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Article
Open AccessRare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report
Developmental dyslexia (DD) is a neurodevelopmental learning disorder with high heritability. A number of candidate susceptibility genes have been identified, some of which are linked to the function of the ci...
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Article
Open AccessAcute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growth
Caffeine is a widely consumed psychoactive substance, but little is known about the effects of caffeine stimulation on global gene expression changes in neurons. Here, we conducted gene expression profiling of...
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Article
Open AccessGenomic sequencing of a dyslexia susceptibility haplotype encompassing ROBO1
The DYX5 locus for developmental dyslexia was mapped to chromosome 3 by linkage study of a large Finnish family, and later, roundabout guidance receptor 1 (ROBO1) was implicated as a candidate gene at DYX5 with s...