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    Chapter and Conference Paper

    Estimating Effects of Extrinsic Noise on Model Genes and Circuits with Empirically Validated Kinetics

    Recent studies of Escherichia coli transcription dynamics using time-lapse confocal microscopy and in vivo single-RNA detection confirmed that transcription initiation has two main rate-limiting steps. Here, we a...

    Samuel M. D. Oliveira in Artificial Life and Evolutionary Computati… (2018)

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    Chapter and Conference Paper

    Modeling and Engineering Promoters with Pre-defined RNA Production Dynamics in Escherichia Coli

    Recent developments in live-cell time-lapse microscopy and signal processing methods for single-cell, single-RNA detection now allow characterizing the in vivo dynamics of RNA production of Escherichia coli promo...

    Samuel M. D. Oliveira, Mohamed N. M. Bahrudeen in Computational Methods in Systems Biology (2018)