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Article
Open AccessChromosome and plasmid-borne PLacO3O1 promoters differ in sensitivity to critically low temperatures
Temperature shifts trigger genome-wide changes in Escherichia coli’s gene expression. We studied if chromosome integration impacts on a gene’s sensitivity to these shifts, by comparing the single-RNA production k...
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Article
Open AccessRate-limiting steps in transcription dictate sensitivity to variability in cellular components
Cell-to-cell variability in cellular components generates cell-to-cell diversity in RNA and protein production dynamics. As these components are inherited, this should also cause lineage-to-lineage variability...