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  1. Article

    Open Access

    Chromosome and plasmid-borne PLacO3O1 promoters differ in sensitivity to critically low temperatures

    Temperature shifts trigger genome-wide changes in Escherichia coli’s gene expression. We studied if chromosome integration impacts on a gene’s sensitivity to these shifts, by comparing the single-RNA production k...

    Samuel M. D. Oliveira, Nadia S. M. Goncalves, Vinodh K. Kandavalli in Scientific Reports (2019)

  2. Article

    Open Access

    Rate-limiting steps in transcription dictate sensitivity to variability in cellular components

    Cell-to-cell variability in cellular components generates cell-to-cell diversity in RNA and protein production dynamics. As these components are inherited, this should also cause lineage-to-lineage variability...

    Jarno Mäkelä, Vinodh Kandavalli, Andre S. Ribeiro in Scientific Reports (2017)