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  1. Article

    Open Access

    Matching-Adjusted Indirect Comparison of Brexucabtagene Autoleucel (ZUMA-2) and Pirtobrutinib (BRUIN) in Patients with Relapsed/Refractory Mantle Cell Lymphoma Previously Treated with a Covalent Bruton Tyrosine Kinase Inhibitor

    Patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) often require multiple lines of treatment and have a poor prognosis, particularly after failing covalent Bruton tyrosine kinase inhibitor (cBT...

    Gilles Salles, Jenny M. H. Chen, Ina Zhang, Fabio Kerbauy in Advances in Therapy (2024)

  2. Article

    Open Access

    Controlling the pandemic during the SARS-CoV-2 vaccination rollout

    There is a consensus that mass vaccination against SARS-CoV-2 will ultimately end the COVID-19 pandemic. However, it is not clear when and which control measures can be relaxed during the rollout of vaccinatio...

    João Viana, Christiaan H. van Dorp, Ana Nunes, Manuel C. Gomes in Nature Communications (2021)

  3. Article

    Open Access

    COVID-19 in a pediatric cohort—retrospective review of chest computer tomography findings

    Radiological features of the novel 2019 coronavirus disease (COVID-19) have been mainly described in adults. Available literature states that imaging findings in children are similar but less pronounced. The a...

    Rita Pina Prata, Ana Forjaco in Egyptian Journal of Radiology and Nuclear … (2021)

  4. No Access

    Article

    Sexual dimorphism of the adult human retina assessed by optical coherence tomography

    Sexual dimorphism in the human visual system is a well-established phenomenon, and recent research has unveiled possible connections between gonadal hormones and the retina status. In the literature, the findi...

    Ana Nunes, Pedro Serranho, Hugo Quental, António F. Ambrósio in Health and Technology (2020)

  5. Article

    Open Access

    Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer’s disease

    Alzheimer’s disease (AD) is a progressive neurodegenerative disorder whose diagnosis remains a notable challenge. The literature suggests that cerebral changes precede AD symptoms by over two decades, implying...

    Hugo Ferreira, João Martins, Ana Nunes, Paula I. Moreira in Health and Technology (2020)

  6. No Access

    Chapter and Conference Paper

    The Effect of Menopause on the Sexual Dimorphism in the Human Retina – Texture Analysis of Optical Coherence Tomography Data

    Sexual dimorphism in the human retina has recently been connected to gonadal hormones. In the study herein presented, texture analysis was applied to computed mean value fundus (MVF) images from optical cohere...

    Ana Nunes, Pedro Serranho, Hugo Quental in Image Analysis and Recognition (2020)

  7. No Access

    Chapter and Conference Paper

    Characterization of the Retinal Changes of the 3xTg-AD Mouse Model of Alzheimer’s Disease

    In this work, we imaged the retina of wild-type and triple-transgenic mice model of Alzheimer’s disease (AD) (3xTg-AD), at the ages of one and two months, by optical coherence tomography. Texture analysis of c...

    Hugo Ferreira, João Martins, Ana Nunes in XV Mediterranean Conference on Medical and… (2020)

  8. No Access

    Chapter and Conference Paper

    Sexual Dimorphism of the Adult Human Retina Assessed by Optical Coherence Tomography

    In this work, we imaged the retina of healthy age-matched female and male subjects with optical coherence tomography to assess the existence of localised sex-related differences in the retina. Texture analysi...

    Ana Nunes, Pedro Serranho, Hugo Quental in XV Mediterranean Conference on Medical and… (2020)

  9. No Access

    Chapter

    Machine Learning Approaches in OCT: Application to Neurodegenerative Disorders

    The use of machine learning (ML) in medicine is gaining momentum. In this chapter, we address the use of optical coherence tomography (OCT) to image the ocular fundus of the human eye, and the ocular fundus of...

    Rui Bernardes, Lília Jorge, Ana Nunes in OCT and Imaging in Central Nervous System … (2020)

  10. Article

    Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory

    The consumption of caffeine modulates working and reference memory through the antagonism of adenosine A2A receptors (A2ARs) controlling synaptic plasticity processes in hippocampal excitatory synapses. Fear memo...

    Ana Patrícia Simões, Nuno J Machado, Nélio Gonçalves in Neuropsychopharmacology (2016)

  11. Article

    Open Access

    Whole body MR-PET: a new internal dosimetry method for radiation transport calculation from biokinetic model data

    Ana Nunes, Francisco Alves, Miguel Patrício in EJNMMI Physics (2014)

  12. Chapter and Conference Paper

    AJITTS: Adaptive Just-In-Time Transaction Scheduling

    Distributed transaction processing has benefited greatly from optimistic concurrency control protocols thus avoiding costly fine-grained synchronization. However, the performance of these protocols degrades si...

    Ana Nunes, Rui Oliveira, José Pereira in Distributed Applications and Interoperable Systems (2013)

  13. No Access

    Book

  14. No Access

    Chapter

    The Set of Planar Orbits of Second Species in the RTBP

    We present a brief summary of the conclusions of our work on the set of orbits of the planar circular restricted three body problem which undergo consecutive close encounters with the small primary, or orbits ...

    Joaquim Font, Ana Nunes, Carles Simó in Dynamics, Games and Science I (2011)

  15. No Access

    Chapter

    Introduction

    In African-American History, Thomas C. Holt states that, although the study of black American history was initiated and developed by African American intellectuals and activists, it was Gunnar Myrdal’s American D...

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

  16. No Access

    Chapter

    Conclusion

    Having as their point of departure the idea that “the past,” as James Baldwin notes, “is all that makes the present coherent, and further, that the past will remain horrible as long as we refuse to assess it ho.....

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

  17. No Access

    Chapter

    Contexts

    My interest here is to consider a number of texts that significantly determined the development of twentieth-century African American women’s writing. Issues from the accuracy of portraits of black American exp.....

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

  18. No Access

    Chapter

    History as Birthmark

    The 1960s witnessed a renewed interest in slave narratives and African American history and culture, and the development of an aesthetics that was politically engaged, highlighted a need for social and economic.....

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

  19. No Access

    Chapter

    “Her Best Thing, Her Beautiful, Magical Best Thing”

    Recent portrayals of the slavery era are dominated by two main trends: the genealogical novel and narratives that use fantastic and magical realist elements in order to represent history. Linda Beatrice Brown’s C...

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

  20. No Access

    Chapter

    Setting the Record Straight

    One of the twentieth-century writers who followed in the steps of her African American literary foremothers, taking into account not only the content and direction of her artistic project but also the course of.....

    Ana Nunes in African American Women Writers’ Historical Fiction (2011)

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