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  1. Article

    Open Access

    The two faces of synaptic failure in AppNL-G-F knock-in mice

    Intensive basic and preclinical research into Alzheimer’s disease (AD) has yielded important new findings, but they could not yet been translated into effective therapies. One of the reasons is the lack of ani...

    Amira Latif-Hernandez, Victor Sabanov, Tariq Ahmed… in Alzheimer's Research & Therapy (2020)

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  2. Article

    Open Access

    Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning

    Aging is associated with loss of circadian immune responses and circadian gene transcription in peripheral macrophages. Microglia, the resident macrophages of the brain, also show diurnal rhythmicity in regula...

    Chinyere Agbaegbu Iweka, Erica Seigneur… in Journal of Neuroinflammation (2023)

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