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  1. No Access

    Article

    KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress

    T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic neoplasm resulting from the malignant transformation of T-cell progenitors. While activating NOTCH1 mutations are the dominant genetic dr...

    Nancy Issa, Hassan Bjeije, Elisabeth R. Wilson, Aishwarya Krishnan… in Leukemia (2023)

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    Article

    Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

    Individuals affected with neurofibromatosis 1 (NF1) harbor increased numbers of GFAP-immunoreactive cerebral astrocytes and develop astrocytomas that can lead to blindness and death. Mice heterozygous for a ta...

    David H Gutmann, Allison Loehr, Yu**g Zhang, Joanna Kim, Mark Henkemeyer… in Oncogene (1999)