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Article
Influence of genetic variants in FADS2 and ELOVL2 genes on BMI and PUFAs homeostasis in children and adolescents with obesity
Several studies identified genetic variants in FADS and ELOVL2 genes associated with obesity-related conditions, such as alterations in blood lipid parameters and insulin homeostasis. The aim of this cross-sectio...
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Article
FADS cluster variants are associated with insulin sensitivity in children and adolescents with overweight and obesity
Changes in the desaturation activity of LC-PUFAs may influence insulin sensitivity by modulating the relative abundance of omega-3. The aim of this cross-sectional study was to assess the association between g...
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Article
Open AccessEarly marker of ocular neurodegeneration in children and adolescents with type 1 diabetes: the contributing role of polymorphisms in mir146a and mir128a genes
Early ocular neurodegenerative signs of diabetic neuropathy (DN) can be found in children and adolescents with type 1 diabetes (T1D). No data are available on the potential role of polymorphisms in miRNAs gene...
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Article
Correction to: A new proposal for a second insulin bolus to optimize postprandial glucose profile in adolescents with type 1 diabetes
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Article
A new proposal for a second insulin bolus to optimize postprandial glucose profile in adolescents with type 1 diabetes
To evaluate whether a second insulin bolus, calculated with a new approach, could improve postprandial glucose (PPG) after the intake of real-life high-fat (HF) and high-protein (HP) mixed meals.
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Article
Open AccessIGF1 and PPARG polymorphisms are associated with reduced estimated glomerular filtration rate in a cohort of children and adolescents with type 1 diabetes
Several genetic loci have been associated with diabetic nephropathy; however, the underlying genetic mechanisms are still poorly understood, with no robust candidate genes identified yet.
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Article
Micronutrients in early life and offspring metabolic health programming: a promising target for preventing non-communicable diseases
Chronic non-communicable diseases are the leading cause of morbidity and mortality worldwide. Develo** and implementing effective preventive strategies is the best way to ensure the overall metabolic health ...
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Article
Postprandial glucose metabolism in children and adolescents with type 1 diabetes mellitus: potential targets for improvement
The main goal of therapeutic management of type 1 Diabetes Mellitus (T1DM) is to maintain optimal glycemic control to prevent acute and long-term diabetes complications and to enable a good quality of life. Po...