11 Result(s)
-
Article
Open AccessSequence similarity is more relevant than species specificity in probabilistic backtranslation
Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module. The degeneracy of the genetic code makes ...
-
Article
Open AccessGraphFind: enhancing graph searching by low support data mining techniques
Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these graph databases, a key role is played by ...
-
Article
Open AccessSING: Subgraph search In Non-homogeneous Graphs
Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image understanding. Since subgraph isomorphism is a c...
-
Article
Open AccessBioinformatics in Italy: BITS2012, the ninth annual meeting of the Italian Society of Bioinformatics
The BITS2012 meeting, held in Catania on May 2-4, 2012, brought together almost 100 Italian researchers working in the field of Bioinformatics, as well as students in the same or related disciplines. About 90 ...
-
Article
Open AccessVIRGO: visualization of A-to-I RNA editing sites in genomic sequences
RNA Editing is a type of post-transcriptional modification that takes place in the eukaryotes. It alters the sequence of primary RNA transcripts by deleting, inserting or modifying residues. Several forms of R...
-
Article
Open AccessA subgraph isomorphism algorithm and its application to biochemical data
Graphs can represent biological networks at the molecular, protein, or species level. An important query is to find all matches of a pattern graph to a target graph. Accomplishing this is inherently difficult ...
-
Article
Open AccessKAOS: a new automated computational method for the identification of overexpressed genes
Kinase over-expression and activation as a consequence of gene amplification or gene fusion events is a well-known mechanism of tumorigenesis. The search for novel rearrangements of kinases or other druggable ...
-
Article
Open AccessINBIA: a boosting methodology for proteomic network inference
The analysis of tissue-specific protein interaction networks and their functional enrichment in pathological and normal tissues provides insights on the etiology of diseases. The Pan-cancer proteomic project, ...
-
Article
Fast Subgraph Matching Strategies Based on Pattern-Only Heuristics
Many scientific applications entail solving the subgraph isomorphism problem, i.e., given an input pattern graph, find all the subgraphs of a (usually much larger) target graph that are structurally equivalent...
-
Article
Open AccessTACITuS: transcriptomic data collector, integrator, and selector on big data platform
Several large public repositories of microarray datasets and RNA-seq data are available. Two prominent examples include ArrayExpress and NCBI GEO. Unfortunately, there is no easy way to import and manipulate d...
-
Article
Open AccessRNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis
RNA-Seq is a well-established technology extensively used for transcriptome profiling, allowing the analysis of coding and non-coding RNA molecules. However, this technology produces a vast amount of data requ...
