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Computational Design in Synthetic Biology

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  1. Article

    Open Access

    Asmparts: assembly of biological model parts

    We propose a new computational tool to produce models of biological systems by assembling models from biological parts. Our software not only takes advantage of modularity, but it also enforces standardisation...

    Guillermo Rodrigo, Javier Carrera, Alfonso Jaramillo in Systems and Synthetic Biology (2007)

  2. Article

    Open Access

    Computational design of digital and memory biological devices

    The use of combinatorial optimization techniques with computational design allows the development of automated methods to design biological systems. Automatic design integrates design principles in an unsuperv...

    Guillermo Rodrigo, Alfonso Jaramillo in Systems and Synthetic Biology (2007)

  3. Article

    Open Access

    Changes in the gene expression profile of Arabidopsis thaliana after infection with Tobacco etch virus

    Tobacco etch potyvirus (TEV) has been extensively used as model system for the study of positive-sense RNA virus infecting plants. TEV ability to infect Arabidopsis thaliana varies among ecotypes. In this study, ...

    Patricia Agudelo-Romero, Pablo Carbonell, Francisca de la Iglesia in Virology Journal (2008)

  4. Article

    Open Access

    PROTDES: CHARMM toolbox for computational protein design

    We present an open-source software able to automatically mutate any residue positions and find the best aminoacids in an arbitrary protein structure without requiring pairwise approximations. Our software, PRO...

    María Suárez, Pablo Tortosa, Alfonso Jaramillo in Systems and Synthetic Biology (2008)

  5. Article

    Synthetic biology gains momentum in Europe

    David Gilbert, Alfonso Jaramillo, Natalio Krasnogor in Systems and Synthetic Biology (2010)