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Article
Open AccessMaternal and cord blood vitamin D level and the infant gut microbiota in a birth cohort study
Mounting evidence suggests both vitamin D and the early life gut microbiome influence childhood health outcomes. However, little is known about how these two important exposures are related. We aimed to examin...
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Article
Open AccessEvaluating methods for combining rare variant data in pathway-based tests of genetic association
Analyzing sets of genes in genome-wide association studies is a relatively new approach that aims to capitalize on biological knowledge about the interactions of genes in biological pathways. This approach, ca...
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Article
Open AccessEvaluating methods for the analysis of rare variants in sequence data
A number of rare variant statistical methods have been proposed for analysis of the impending wave of next-generation sequencing data. To date, there are few direct comparisons of these methods on real sequenc...