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Exploring the knowledge, attitudes, and practices on sexual and gender minorities patients: a survey on Italian Neurologists
Sexual and gender minorities (SGM) encompass individuals identifying as lesbian, gay, bisexual, transgender, and queer (LGBTQ). SGM patients experience difficulties in accessing healthcare and may face discrim...
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Article
Open AccessCan mobile health apps with smartphones and tablets be the new frontier of cognitive rehabilitation in older individuals? A narrative review of a growing field
A recent interesting field of application of telemedicine/e-health involved smartphone apps. Although research on mHealth began in 2014, there are still few studies using these technologies in healthy elderly ...
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Article
Open AccessGender differences in non-motor fluctuations in Parkinson’s disease
Non-motor symptoms (NMS) and Non-motor fluctuations (NMF) in Parkinson’s Disease (PD) are common, involving several domains and affecting quality of life. Aim of the study is to estimate the burden of NMF in P...
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Article
Influence of RBD onset on the clinical characteristics of Parkinson’s disease patients: a retrospective study
In Parkinson’s disease (PD), rapid eye movement (REM) sleep behavior disorder (RBD) might either precede the appearance of motor symptoms, or develop during the disease course. PD patients with RBD are charact...
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Article
Open AccessCorrection to: The Italian tremor Network (TITAN): rationale, design and preliminary findings
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Open AccessCorticobasal syndrome and Parkinson’s disease at the beginning: asymmetrical patterns of MRI and Blink Reflex for early diagnosis
Differential diagnosis between Parkinson’s disease (PD) and corticobasal syndrome (CBS) could be challenging at the early stage, due to the asymmetric onset of both diseases. Despite the clinical overlap, the ...
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Article
Open AccessDo demographic and clinical features and comorbidities affect the risk of spread to an additional body site in functional motor disorders?
The aim of this study is to assess changes in the body distribution and the semeiology of functional motor disorder (FMD) in patients who reported only one or more than one body site affected at FMD onset. Dat...
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Article
Open AccessThe Italian tremor Network (TITAN): rationale, design and preliminary findings
The recently released classification has revised the nosology of tremor, defining essential tremor (ET) as a syndrome and fueling an enlightened debate about some newly conceptualized entities such as ET-plus....
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Open AccessExecutive functioning and serum lipid fractions in Parkinson’s disease—a possible sex-effect: the PACOS study
The association between dyslipidemia and cognitive performance in Parkinson’s disease (PD) patients still needs to be clarified. Aim of the study was to evaluate the presence of possible associations between s...
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Article
Burden of Parkinson’s disease in Sicily: a health administrative database study
Prevalence of Parkinson’s disease (PD) increases with the advanced ages, representing a relevant health burden. Accurate prevalence estimates are of fundamental need in order to adjust the supply of health ser...
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Article
Pure sensitive chronic inflammatory axonal polyneuropathy following Pfizer COVID-19 vaccine
During the worldwide mass vaccination campaign against SARS-CoV-2, multiple side effects have been observed. We described the case of a patient who developed pure sensitive chronic inflammatory axonal polyneur...
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Article
Open AccessFunctional motor phenotypes: to lump or to split?
Functional motor disorders (FMDs) are usually categorized according to the predominant phenomenology; however, it is unclear whether this phenotypic classification mirrors the underlying pathophysiologic mecha...
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Article
Open AccessStructural MRI substrate of long-duration response to levodopa in Parkinson’s disease: an exploratory study
The long-duration response (LDR) to L-dopa is a sustained benefit deriving from chronic administration of therapy to patients with Parkinson’s disease (PD). Almost all patients with early PD may develop the LDR t...
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Article
Neuroanatomical changes in early Parkinson’s disease with mild cognitive impairment: a VBM study; the Parkinson’s Disease Cognitive Impairment Study (PaCoS)
Mild cognitive impairment (MCI) is common in Parkinson’s disease (PD), but the underlying pathological mechanism has not been fully understood. Voxel-based morphometry could be used to evaluate regional atroph...
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Article
Acute motor effects induced by opioid antagonists in Parkinson’s disease: could naloxone be a rescue therapy?
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Article
iNPH with parkinsonism: response to lumbar CSF drainage and ventriculoperitoneal shunting
To evaluate clinical response after external lumbar drainage (ELD) and ventriculoperitoneal shunting (VPS) in a cohort of patients with idiopathic normal pressure hydrocephalus associated with parkinsonism (iN...
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Article
Open AccessVascular risk factors, white matter lesions and cognitive impairment in Parkinson’s disease: the PACOS longitudinal study
Vascular risk factors (VRFs) may be associated with cognitive decline in early Parkinson’s disease (PD) but results are inconclusive. The identification of modifiable risk factors is relevant for prevention an...
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Article
Base-peak assessment of levodopa response and detection of fluctuating patients in Parkinson’s disease
This study aims to evaluate the base-peak difference in levodopa response for detecting patients with motor fluctuations in Parkinson’s disease (PD).
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Article
Open AccessTranscranial random noise stimulation over the primary motor cortex in PD-MCI patients: a crossover, randomized, sham-controlled study
Mild cognitive impairment (MCI) is a very common non-motor feature of Parkinson’s disease (PD) and the non-amnestic single-domain is the most frequent subtype. Transcranial random noise stimulation (tRNS) is a...
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Article
Asymmetry index of Blink Reflex Recovery Cycle differentiates Parkinson’s disease from atypical Parkinsonian syndromes
Differential diagnosis between Parkinson’s disease (PD) and atypical Parkinsonian syndromes (APS), such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP), is often difficult because of ...