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Comparison of double-flap and OrVil techniques of laparoscopy-assisted proximal gastrectomy in preventing gastroesophageal reflux: a retrospective cohort study

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  1. Article

    A phase II study of neoadjuvant chemotherapy with docetaxel, cisplatin, and S-1, followed by gastrectomy with D2 lymph node dissection for high-risk advanced gastric cancer: results of the KDOG1001 trial

    The prognosis of patients with gastric cancer with bulky node metastasis, linitis plastica (type 4), or large ulcero-invasive-type tumors (type 3) remains poor. We conducted a phase II study to evaluate the sa...

    Kei Hosoda, Mizutomo Azuma, Chikatoshi Katada, Hiromitsu Moriya in Gastric Cancer (2019)

  2. Article

    Open Access

    Expression of KK-LC-1, a cancer/testis antigen, at non-tumour sites of the stomach carrying a tumour

    Kita-Kyushu lung cancer antigen-1 (KK-LC-1) is a cancer/testis antigen (CTA) and predominant target for cancer immunotherapy. Our previous study indicated that KK-LC-1 was expressed in 82% of gastric cancers, ...

    Takashi Fukuyama, Nobue Futawatari, Rui Yamamura, Taiga Yamazaki in Scientific Reports (2018)

  3. Article

    DNA diagnosis of peritoneal fluid cytology test by CDO1 promoter DNA hypermethylation in gastric cancer

    Minimal residual disease of the peritoneum is challenging for early cancer detection in gastric cancer (GC). Utility of PCR amplification of cancer-derived DNA has been considered feasible due to its molecular...

    Hideki Ushiku, Keishi Yamashita, Akira Ema, Naoko Minatani in Gastric Cancer (2017)

  4. Article

    Prognostic impact of venous invasion in stage IB node-negative gastric cancer

    Little is known about risk factors for recurrence in stage IB gastric cancer without lymph node metastasis. The aims of this study were to determine prognostic factors associated with long-term survival and to...

    Ippeita Araki, Kei Hosoda, Keishi Yamashita, Natsuya Katada in Gastric Cancer (2015)

  5. Article

    Lymph node ratio is a critical prognostic predictor in gastric cancer treated with S-1 chemotherapy

    S-1 is an oral anticancer drug widely used in postoperative adjuvant therapy for patients in Japan with stage II/III gastric cancer. Candidates for more intense adjuvant treatments need to be identified, parti...

    Akira Ema, Keishi Yamashita, Shinich Sakuramoto, Guoqin Wang in Gastric Cancer (2014)

  6. Article

    Open Access

    Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

    We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggre...

    Mina Waraya, Keishi Yamashita, Hiroshi Katoh, Akira Ooki, Hiroshi Kawamata in BMC Cancer (2012)