8 Result(s)
within
Akinori Nishi
Life Sciences
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Article
Open AccessSLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex
SLITRK1 is an obsessive-compulsive disorder spectrum-disorders-associated gene that encodes a neuronal transmembrane protein. Here we show that SLITRK1 suppresses noradrenergic projections in the neonatal prefron...
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Article
Open AccessEphedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity
Although respiratory syncytial virus (RSV) is a major cause of respiratory tract infection in children, no effective therapies are available. Recently, RSV G, the attachment glycoprotein, has become a major fo...
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Article
Open AccessPublisher Correction: LimeMap: a comprehensive map of lipid mediator metabolic pathways
A Correction to this paper has been published: https://doi.org/10.1038/s41540-021-00174-w
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Article
Open AccessLimeMap: a comprehensive map of lipid mediator metabolic pathways
Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associati...
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Article
Open AccessDifferential annotation of converted metabolites (DAC-Met): Exploration of Maoto (Ma-huang-tang)-derived metabolites in plasma using high-resolution mass spectrometry
Traditional herbal medicine (THM) contains a vast number of natural compounds with varying degrees of pharmacological activity. To elucidate the mode of action, comprehensive metabolite profiling in the plasma...
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Open AccessDeconstructing the traditional Japanese medicine “Kampo”: compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms
Pharmacological activities of the traditional Japanese herbal medicine (Kampo) are putatively mediated by complex interactions between multiple herbal compounds and host factors, which are difficult to charact...
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Open AccessQTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains
The activity of mice in their home cage is influenced greatly by the cycle of light and dark. In addition, home-cage activity shows remarkable time-dependent changes that result in a prominent temporal pattern...
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Article
Open AccessQTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains
A variety of mouse strains exhibit diversity in spontaneous activity consistent with an important genetic contribution. To date, many studies have defined spontaneous home-cage activity as total distance or to...
