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  1. No Access

    Article

    Regulatory T cells function at the early stage of tumor progression in a mouse model of tongue squamous cell carcinoma

    The objective of this study was to observe the distribution of regulatory T cells (Tregs) in the development of tongue squamous cell carcinoma (SCC) and to determine the role of Tregs in the progression of ton...

    Kentaro Miki, Yorihisa Orita, Yuka Gion, Soshi Takao in Cancer Immunology, Immunotherapy (2016)

  2. Article

    Open Access

    Low prevalence of human mammary tumor virus (HMTV) in breast cancer patients from Myanmar

    Human mammary tumor virus (HMTV) is 90–95% homologous to mouse mammary tumor virus (MMTV), one of the causal agents of murine mammary tumors. HMTV (MMTV-like) sequences were reported to be present in human bre...

    Thar Htet San, Masayoshi Fujisawa, Soichiro Fushimi in Infectious Agents and Cancer (2017)

  3. Article

    Open Access

    Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer

    Patients with triple-negative breast cancer (TNBC) often have poorer prognosis than those with other subtypes because of its aggressive behaviors. Cancer cells are heterogeneous, and only a few highly metastat...

    Chunning Li, Teizo Yoshimura, Miao Tian, Yuze Wang in Breast Cancer Research (2022)

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    Article

    Comparison of therapeutic features and oncologic outcome in patients with pN1 prostate cancer among robot-assisted, laparoscopic, or open radical prostatectomy

    To compare the therapeutic features and oncological outcomes of robot-assisted radical prostatectomy (RARP) with those of open radical prostatectomy (ORP) or laparoscopic radical prostatectomy (LRP) in lymph n...

    Takahiro Kirisawa, Masaki Shiota in International Journal of Clinical Oncology (2023)

  5. Article

    Open Access

    Updated systematic review and network meta-analysis of first-line treatments for metastatic renal cell carcinoma with extended follow-up data

    Immune checkpoint inhibitor (ICI)-based combination therapies are the recommended first-line treatment for metastatic renal cell carcinoma (mRCC). However, no head-to-head phase-3 randomized controlled trials ...

    Takafumi Yanagisawa, Keiichiro Mori, Akihiro Matsukawa in Cancer Immunology, Immunotherapy (2024)

  6. No Access

    Article

    Survival outcome of chemotherapy-naïve castration-resistant prostate cancer treated with new-generation androgen receptor axis-targeted agents in real-world analysis

    The androgen receptor axis-targeted (ARAT) agents abiraterone and enzalutamide have been introduced against castration-resistant prostate cancer (CRPC). However, determining which of these agents should be use...

    Tatsuya Shimomura, Keiichiro Mori in International Journal of Clinical Oncology (2024)

  7. Article

    Open Access

    Impact of disease volume on survival efficacy of triplet therapy for metastatic hormone-sensitive prostate cancer: a systematic review, meta-analysis, and network meta-analysis

    Triplet therapy, androgen receptor signaling inhibitors (ARSIs) plus docetaxel plus androgen-deprivation therapy (ADT), is a novel guideline-recommended treatment for metastatic hormone-sensitive prostate canc...

    Akihiro Matsukawa, Pawel Rajwa in International Journal of Clinical Oncology (2024)

  8. No Access

    Article

    Prognosis based on postoperative PSA levels and treatment in prostate cancer with lymph node involvement

    The therapeutic role of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) for prostate cancer is not established. In clinical practice, PLND is primarily performed in cases of high-risk pro...

    Tokiyoshi Tanegashima, Masaki Shiota in International Journal of Clinical Oncology (2024)