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Open AccessValidation and refinement of cropland map in southwestern China by harnessing ten contemporary datasets
Accurate cropland map serves as the cornerstone of effective agricultural monitoring. Despite the continuous enrichment of remotely sensed cropland maps, pervasive inconsistencies have impeded their further ap...
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Article
Open AccessExploring prognostic values of DNA ploidy, stroma-tumor fraction and nucleoty** in stage II colon cancer patients
To assess the prognostic value of three novel biomarkers, DNA ploidy, stroma-tumor fraction, and nucleoty**, seeking for more accurate stratification in stage II colon cancer.
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Open AccessPara-selective nitrobenzene amination lead by C(sp2)-H/N-H oxidative cross-coupling through aminyl radical
Arylamines, serving as crucial building blocks in natural products and finding applications in multifunctional materials, are synthesized on a large scale via an electrophilic nitration/reduction sequence. How...
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Article
Open AccessMotif-based community detection in heterogeneous multilayer networks
Multilayer networks composed of intralayer edges and interlayer edges are an important type of complex networks. Considering the heterogeneity of nodes and edges, it is necessary to design more reasonable and ...
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Article
Open AccessOCTN2- and ATB0,+-targeted nanoemulsions for improving ocular drug delivery
Traditional eye drops are administered via topical instillation. However, frequent dosing is needed due to their relatively rapid precorneal removal and low ocular bioavailability. To address these issues, ste...
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Article
Open AccessDownregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis
Macrophage-derived extracellular vesicle (macrophage-EV) is highly studied for its regulatory role in atherosclerosis (AS). Our current study tried to elucidate the possible role of macrophage-EV loaded with s...
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Article
Open AccessAtypical brain lateralization for speech processing at the sublexical level in autistic children revealed by fNIRS
Autistic children often exhibit atypical brain lateralization of language processing, but it is unclear what aspects of language contribute to this phenomenon. This study employed functional near-infrared spec...
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Article
Open AccessNatural products targeting the MAPK-signaling pathway in cancer: overview
This article summarizes natural products that target the MAPK-signaling pathway in cancer therapy. The classification, chemical structures, and anti-cancer mechanisms of these natural products are elucidated, ...
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Article
Open AccessExperimental study on the gas desorption law in coal affected by dynamic water injection
Water from hydraulic technology affects the desorption of gas from coal seams. Gas desorption behavior is critical information for gas control in coal mines. In this study, a designed coal seam water injection...
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Article
Open AccessEnhanced and synergistic catalytic activation by photoexcitation driven S−scheme heterojunction hydrogel interface electric field
The regulation of heterogeneous material properties to enhance the peroxymonosulfate (PMS) activation to degrade emerging organic pollutants remains a challenge. To solve this problem, we synthesize S−scheme h...
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Article
Open AccessResearch on charge induction law and application of coal samples with different fissures
Indoor testing are performed to explore the charge induction law during the uniaxial compression fracture process of coal samples, and the charge time and frequency domain signals of coal samples with differen...
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Open AccessAuthor Correction: 3D smooth path planning of AUV based on improved ant colony optimization considering heading switching pressure
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Article
Open AccessValve turning towards on-cycle in cobalt-catalyzed Negishi-type cross-coupling
Ligands and additives are often utilized to stabilize low-valent catalytic metal species experimentally, while their role in suppressing metal deposition has been less studied. Herein, an on-cycle mechanism is...
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Open Access3D smooth path planning of AUV based on improved ant colony optimization considering heading switching pressure
A smooth and secure spatial path planning algorithm that integrates the improved ant colony optimization with the corrective connected spatial search strategy is proposed, aiming at heavy heading switching pre...
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Article
Open AccessFailure characteristics and conditions of rock-coal combination structure with weak layer under dynamic and static stresses
To comprehensively understand the mechanical response of a rock-coal combination structure containing a weak layer, a series of laboratory static loading and impact loading experiments were conducted. The resu...
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Article
Open AccessEvaluation of a community-based integrated care model (CIE) for frail older people in rural Foshan, China: study protocol for a stepped-wedge cluster randomized controlled trial {1}
While community-based eldercare has proven to be effective in qualitative studies, there is limited evidence on the effectiveness of this geriatric care model in rural communities where caring for older people...
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Open AccessElectrochemical oxidative difunctionalization of diazo compounds with two different nucleophiles
With the fast development of synthetic chemistry, the introduction of functional group into organic molecules has attracted increasing attention. In these reactions, the difunctionalization of unsaturated bond...
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Article
Open AccessConformation-dependent dynamic organic phosphorescence through thermal energy driven molecular rotations
Organic room-temperature phosphorescent (RTP) materials exhibiting reversible changes in optical properties upon exposure to external stimuli have shown great potential in diverse optoelectronic fields. Partic...
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Article
Open AccessSurvival outcomes of stage I colorectal cancer: development and validation of the ACEPLY model using two prospective cohorts
Approximately 10% of stage I colorectal cancer (CRC) patients experience unfavorable clinical outcomes after surgery. However, little is known about the subset of stage I patients who are predisposed to high r...
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Open AccessThe chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling
Chromodomain helicase DNA binding protein (CHD) family plays critical roles in regulating gene transcription. The family is linked to cancer disease, but the family member’s role in tumorigenesis remains largely ...