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Chapter
The Role of Gut Microbiota in the Antidepressant Effects of Ketamine
In recent years, the prevalence, mental disability, and suicide rates of depression have been increasing without a corresponding significant change in cure rate, making depression the second largest disease bu...
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Article
Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression
Basic and clinical studies have reported rapid and long-lasting antidepressant effects of ketamine. Although previous studies have proposed several mechanisms underlying the antidepressant effects of ketamine,...
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Article
Postoperative cognitive dysfunction in the aged: the collision of neuroinflammaging with perioperative neuroinflammation
The aging population is burgeoning globally and this trend presents great challenges to the current healthcare system as the growing number of aged individuals receives procedures of surgery and anesthesia. Po...
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Article
PGC-1α–FNDC5–BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat
Skeletal muscle consumes two thirds of the body’s energy and may play a role in stress-related disorders. Evidence suggests that the peroxisome proliferator-activated receptor γ coactivator α (PGC-1α)–fibronec...
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Article
Effect of Propofol on the Expression of MMP-9 and Its Relevant Inflammatory Factors in Brain of Rat with Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is bleeding in brain caused by the rupture of brain blood vessel, which may lead to patient unconsciousness or death. In this study, we measured the expression of matrix metallo...