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  1. No Access

    Article

    The Cl−/HCO3− exchanger pendrin is downregulated during oral co-administration of exogenous mineralocorticoid and KCl in patients with primary aldosteronism

    In primary aldosteronism (PA), the occurrence of K+ loss and hypertension suggest alterations in renal tubular transport, but the molecular basis of these alterations in humans is unclear. In this study, urinary ...

    Aihua Wu, Martin J. Wolley, Qi Wu, Richard D. Gordon… in Journal of Human Hypertension (2021)

  2. No Access

    Article

    The interplay of renal potassium and sodium handling in blood pressure regulation: critical role of the WNK-SPAK-NCC pathway

    Renal salt handling has a profound effect on body fluid and blood pressure (BP) maintenance as exemplified by the use of diuretic medications to treat states of volume expansion or hypertension. It has recentl...

    Aihua Wu, Martin Wolley, Michael Stowasser in Journal of Human Hypertension (2019)