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    Article

    Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation

    The histone H3 lysine 36 methyltransferase SETD2 is frequently mutated in various cancers, including leukemia. However, there has not been any functional model to show the contribution of SETD2 in hematopoiesi...

    Yuan-Liang Zhang, Jie-Wen Sun, Yin-Yin **e, Yan Zhou, ** Liu in Cell Research (2018)

  2. Article

    Open Access

    Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis

    The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk, respectively, under different stresses. This close interconnec...

    Fan Zhang, Qi-Yu Zeng, Hao Xu, Ai-Ning Xu, Dian-Jia Liu, Ning-Zhe Li in Cell Discovery (2021)