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303 Result(s)
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Article
Solid solution strategy modulated defects engineering of (Cr1-xVx)2AlC MAX phase toward superior electromagnetic wave absorption
Defects engineering is an effective strategy for manipulating electromagnetic parameters and enhancing electromagnetic wave (EMW) absorption capacity. However, the relationship between them is not clear, espec...
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Article
Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Article
Chinese Medicine Prolongs Overall Survival of Chinese Patients with Advanced Gastric Cancer: Treatment Pattern and Survival Analysis of a 20-Year Real-World Study
To describe the treatment patterns and survival status of advanced gastric cancer (AGC) in China in the past two decades, and objectively evaluate the impact of standardized Chinese medicine (CM) treatment on ...
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Article
Stepped-up development of accelerator mass spectrometry method for the detection of 60Fe with the HI-13 tandem accelerator
The Moon provides a unique environment for investigating nearby astrophysical events such as supernovae. Lunar samples retain valuable information from these events, via detectable long-lived “fingerprint” rad...
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Open AccessPreparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein
Many proteins of African swine fever virus (ASFV, such as p72, p54, p30, CD2v, K205R) have been successfully expressed and characterized. However, there are few reports on the DP96R protein of ASFV, which is t...
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Article
Open AccessCorrection: Reduction of NgR in perforant path decreases amyloid-β peptide production and ameliorates synaptic and cognitive deficits in APP/PS1 mice
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Open AccessExploring the chemical components of Kuanchang-Shu granule and its protective effects of postoperative ileus in rats by regulating AKT/HSP90AA1/eNOS pathway
Postoperative ileus (POI) is a common obstruction of intestinal content passage caused by almost all abdominal operations that seriously strokes the quality of life of patients. Kuanchang-Shu granule (KCSG), a...
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Article
Open AccessMacro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma
Intratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma. Here, we examine the sing...
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Open AccessPublisher Correction: Psittacosis caused severe community-acquired pneumonia accompanied by acute hypoxic respiratory failure: a multicenter retrospective cohort study from China
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Article
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice
Administration of CHK1-targeted anticancer therapies is associated with an increased cumulative risk of cardiac complications, which is further amplified when combined with gemcitabine. However, the underlying...
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Article
Open AccessCorrection: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma
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Article
Open AccessComprehensive characterization of TGFB1 across hematological malignancies
TGFB1, which encodes TGF-β1, a potent cytokine regulating varies cellular processes including immune responses. TGF-β1 plays context-dependent roles in cancers and is increasingly recognized as a therapeutic targ...
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Article
Plasma Nitrogen Fixation: NOx Synthesis in MnOx/Al2O3 Packed-Bed Dielectric Barrier Discharge
The plasma nitrogen fixation for NOx synthesis from N2 and O2 in MnOx/Al2O3 packed-bed dielectric barrier discharge (DBD) and an enhanced effect of MnOx/Al2O3 catalyst are reported. At N2 content of 50% and SEI o...
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Article
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function
Clinically, cardiac dysfunction is a key component of sepsis-induced multi-organ failure. Mitochondria are essential for cardiomyocyte homeostasis, as disruption of mitochondrial dynamics enhances mitophagy an...
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Article
Open AccessS1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway
Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate rec...
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Article
Tumor cell membrane remodeling with universal ligand for CAR-T cells to inhibit solid tumors
Heterogeneity is a major obstacle to the success of CAR-T therapy in treating solid tumors. The complex tumor microenvironment and varying phenotypes of tumor cells might result in antigen escape, drug resista...
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Article
Open AccessEffect of Contents, Tensile Strengths and Aspect Ratios of Hooked-End Steel Fibers (SFs) on Compressive and Flexural Performance of Normal Strength Concrete
This study is a part of the study to simplify the reinforcing details of reinforced concrete (RC) structural members by substituting the conventional reinforcement with hooked-end steel fibers (SFs). This pape...
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Open AccessPsittacosis caused severe community-acquired pneumonia accompanied by acute hypoxic respiratory failure: a multicenter retrospective cohort study from China
Psittacosis can cause severe community-acquired pneumonia (CAP). The clinical manifestations of psittacosis range from subclinical to fulminant psittacosis with multi-organ failure. It is essential to summariz...
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Article
Effect of Shengmai Yin on Epithelial-Mesenchymal Transition of Nasopharyngeal Carcinoma Radioresistant Cells
To investigate the mechanism by which Chinese medicine Shengmai Yin (SMY) reverses epithelial-mesenchymal transition (EMT) through lipocalin-2 (LCN2) in nasopharyngeal carcinoma (NPC) cells CNE-2R.
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Article
Mechanism of subsidence-buckling and instability of slopes in thick-layered rigid rock under mining
The deformation and failure of mining slopes in layered rocks predominantly result from shear landslides. However, the instability process of the Pusa rock avalanche in Guizhou, China, revealed a unique damage...