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Article
Open AccessBurden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival
Tumor mutational burden (TMB; the quantity of aberrant nucleotide sequences a given tumor may harbor) has been associated with response to immune checkpoint inhibitor therapy and is gaining broad acceptance as...
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Article
Erratum: Cloud computing for genomic data analysis and collaboration
Nature Reviews Genetics doi:10.1038/nrg.2017.113 (2018) The above article originally stated “FireCloud and CGC rely on AWS and the Google Cloud Platform for computing and data storage. In addition to charges f...
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Article
Open AccessPopulation-level distribution and putative immunogenicity of cancer neoepitopes
Tumor neoantigens are drivers of cancer immunotherapy response; however, current prediction tools produce many candidates requiring further prioritization. Additional filtration criteria and population-level u...
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Article
Cloud computing for genomic data analysis and collaboration
Cloud computing is a paradigm whereby computational resources such as computers, storage and bandwidth can be rented on a pay-for-what-you-use basis.
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