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Cloud computing for genomic data analysis and collaboration

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  1. Article

    Open Access

    Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival

    Tumor mutational burden (TMB; the quantity of aberrant nucleotide sequences a given tumor may harbor) has been associated with response to immune checkpoint inhibitor therapy and is gaining broad acceptance as...

    Mary A. Wood, Benjamin R. Weeder, Julianne K. David, Abhinav Nellore in Genome Medicine (2020)

  2. Article

    Erratum: Cloud computing for genomic data analysis and collaboration

    Nature Reviews Genetics doi:10.1038/nrg.2017.113 (2018) The above article originally stated “FireCloud and CGC rely on AWS and the Google Cloud Platform for computing and data storage. In addition to charges f...

    Ben Langmead, Abhinav Nellore in Nature Reviews Genetics (2018)

  3. Article

    Open Access

    Population-level distribution and putative immunogenicity of cancer neoepitopes

    Tumor neoantigens are drivers of cancer immunotherapy response; however, current prediction tools produce many candidates requiring further prioritization. Additional filtration criteria and population-level u...

    Mary A. Wood, Mayur Paralkar, Mihir P. Paralkar, Austin Nguyen in BMC Cancer (2018)