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    Article

    Prenatal cannabis exposure, the brain, and psychopathology during early adolescence

    Prenatal cannabis exposure (PCE) is associated with mental health problems in early adolescence, but the possible neurobiological mechanisms remain unknown. In a large longitudinal sample of adolescents (ages ...

    David A. A. Baranger, Alex P. Miller, Aaron J. Gorelik in Nature Mental Health (2024)

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    Article

    Genetics, epigenetics, and neurobiology of childhood-onset depression: an umbrella review

    Depression is a serious and persistent psychiatric disorder that commonly first manifests during childhood. Depression that starts in childhood is increasing in frequency, likely due both to evolutionary trend...

    Manpreet K. Singh, Aaron J. Gorelik, Christopher Stave in Molecular Psychiatry (2024)

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    Article

    Evaluating efficiency and accuracy of deep-learning-based approaches on study selection for psychiatry systematic reviews

    Scientific publications in mental health are rapidly growing in number and complexity, making curation of abstracts for systematic reviews increasingly time consuming and challenging. As a result, systematic r...

    Aaron J. Gorelik, Mark G. Gorelik, Kathryn K. Ridout in Nature Mental Health (2023)

  4. No Access

    Article

    Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities

    Alcohol expectancies (AEs) are associated with likelihood of alcohol initiation and subsequent alcohol use disorders. It is unclear whether genetic predisposition to alcohol use and/or related traits contribut...

    Emma C. Johnson, Sarah E. Paul, David A. A. Baranger in Behavior Genetics (2023)

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    Article

    A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study

    Genetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present dur...

    Aaron J. Gorelik, Sarah E. Paul, Nicole R. Karcher, Emma C. Johnson in Behavior Genetics (2023)

  6. Article

    Open Access

    Neural correlates of reward processing distinguish healthy youth at familial risk for bipolar disorder from youth at familial risk for major depressive disorder

    Youth at familial risk for bipolar disorder (BD-risk) and major depressive disorder (MDD-risk) have aberrant reward processing, a core feature of these mood disorders. Whether BD risk differentiates from MDD r...

    Akua F. Nimarko, Aaron J. Gorelik, Kayla E. Carta in Translational Psychiatry (2022)