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13 Result(s)

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  1. No Access

    Chapter and Conference Paper

    Contribution of raised ICP and hypotension to CPP reduction in severe brain injury: correlation to outcome

    The aim of this study was to determine to what degree hypotension and ICP contribute to the reduction of cerebral perfusion pressure (CPP), particularly in light of the shift in emphasis to CPP management by t...

    A. Marmarou, A. Saad, G. Aygok… in Intracranial Pressure and Brain Monitoring XII (2005)

  2. No Access

    Chapter and Conference Paper

    Mitochondrial injury measured by proton magnetic resonance spectroscopy in severe head trauma patients

    The aim of this study was to evaluate the extent of mitochondrial injury by assessing N-Acetyl-Aspartate by MR spectroscopy in head injured patients and relating the extent of mitochondrial injury to outcome. ...

    A. Marmarou, S. Signoretti, P. Fatouros… in Intracranial Pressure and Brain Monitoring… (2005)

  3. No Access

    Chapter and Conference Paper

    Guidelines for management of idiopathic normal pressure hydrocephalus: progress to date

    The aim of this project was to develop evidenced based guidelines for the diagnosis and management of idiopathic normal pressure hydrocephalus (iNPH). An advisory panel consisting of the authors assisted by in...

    A. Marmarou, P. Black, M. Bergsneider… in Intracranial Pressure and Brain Monitoring… (2005)

  4. No Access

    Chapter and Conference Paper

    Mortality from traumatic brain injury

    It is the general sense that mortality has been decreasing in recent years compared to earlier studies described by the NIH traumatic coma data bank. We studied mortality during the period of 1984 to 1996 to d...

    J. Lu, A. Marmarou, S. Choi, A. Maas… in Intracranial Pressure and Brain Monitoring… (2005)

  5. No Access

    Chapter and Conference Paper

    The importance of translational research in brain injury

    Progress in the understanding of the pathophysiologic process and management of brain injury provides a unique challenge to the young investigator. Currently, there are teams both in the laboratory and clinica...

    A. Marmarou in Intracranial Pressure and Brain Monitoring XII (2005)

  6. No Access

    Chapter and Conference Paper

    Three-year outcome of shunted idiopathic NPH patients

    The incidence of idiopathic normal pressure hydrocephalus (iNPH) has increased as a result of improved longevity. This report describes the 3-year outcome of shunted iNPH patients compared to three-month outco...

    G. Aygok, A. Marmarou, H. F. Young in Intracranial Pressure and Brain Monitoring XII (2005)

  7. No Access

    Chapter and Conference Paper

    Clinical trials in traumatic brain injury: current problems and future solutions

    Over the past decade many neuroprotective agents have been developed with the hope of being able to improve outcome in patients with traumatic brain injury. Unfortunately, none of the phase III trials performe...

    Dr. A. I. R. Maas, A. Marmarou, G. D. Murray… in Mechanisms of Secondary Brain Damage from … (2004)

  8. No Access

    Chapter and Conference Paper

    Comparison of NAA Measures by MRS and HPLC

    This work investigates the accuracy of an in vivo estimation of absolute N-acetyl aspartate (NAA) concentrations by magnetic resonance spectroscopy (MRS) using cerebral water as an internal reference standard....

    P. P. Fatouros Ph.D., D. L. Heath, A. Beaumont, F. D. Corwin… in Brain Edema XI (2000)

  9. No Access

    Book and Conference Proceedings

    Neuromonitoring in Brain Injury

    R. Bullock, A. Marmarou, B. Alessandri… in Acta Neurochirurgica Supplements (1999)

  10. No Access

    Chapter and Conference Paper

    CSF and ECF Glutamate Concentrations in Head Injured Patients

    Excitatory Amino Acids (EAAs) release has been considered to be neurotoxic in traumatic brain injury patients. Microdialysis samples of extracellular space (ECS) and high glutamate concentrations in cerebrospi...

    T. Yamamoto, S. Rossi, M. Stiefel, E. Doppenberg… in Neuromonitoring in Brain Injury (1999)

  11. No Access

    Chapter and Conference Paper

    Biphasic Pathophysiological Response of Vasogenic and Cellular Edema in Traumatic Brain Swelling

    The objective of this study was to quantify the temporal water content changes and document the type of edema (cellular versus vasogenic) that is occurring during both the acute and the late stages of edema de...

    P. Barzó, A. Marmarou, P. Fatouros, K. Hayasaki, F. Corwin in Brain Edema X (1997)

  12. No Access

    Chapter and Conference Paper

    Traumatic Brain Tissue Acidosis: Experimental and Clinical Studies

    We have been focusing on potential metabolic derangement associated with severe head injury and a clinical trial directed toward treating brain tissue acidosis is currently underway. More specifically, we base...

    A. Marmarou, R. Holdaway, J. D. Ward, K. Yoshida… in Mechanisms of Secondary Brain Damage (1993)

  13. No Access

    Chapter and Conference Paper

    Experimental Studies for Use of Magnetic Resonance in Brain Water Measurements

    The accurate description and quantification of altered brain water resulting from different pathologic conditions is of critical clinical importance. In this work we determined the influence of total water con...

    P. Fatouros Ph.D., A. Marmarou in Brain Edema VIII (1990)