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  1. No Access

    Chapter

    Mechanisms of Synergism Between Gemcitabine and Cisplatin

    2′,2′-difluorodeoxycytidine (Gemcitabine, dFdC) is an antineoplastic agent with clinical activity against several cancer types.1 cis-Diamminedichloroplatinum (cisplatin, CDDP) is a drug with long established anti...

    C. J. A. van Moorsel, G. Veerman… in Purine and Pyrimidine Metabolism in Man IX (1998)

  2. No Access

    Chapter

    Differential Effects of Gemcitabine on Nucleotide Pools of 19 Solid Tumor Cell Lines

    2,2-Difluorodeoxycytidine (dFdC, Gemcitabine, Gemzar) is a deoxycytidine analogue, which is very active against murine experimental tumor models, human tumor xenografts and in clinical Phase II studies.1'2 After ...

    C. J. A. van Moorsel, G. Veerman… in Purine and Pyrimidine Metabolism in Man IX (1998)