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  1. Article

    Open Access

    Wake-Promoting and EEG Spectral Effects of Modafinil After Acute or Chronic Administration in the R6/2 Mouse Model of Huntington’s Disease

    Huntington’s disease (HD) is characterised by progressive symptoms including cognitive deficits and sleep/wake disturbances reflected in an abnormal electroencephalography (EEG). Modafinil, a wake-promoting an...

    Szilvia Vas, Jackie M. Casey, Will T. Schneider, Lajos Kalmar in Neurotherapeutics (2020)

  2. Article

    Open Access

    Indices of comparative cognition: assessing animal models of human brain function

    Understanding the cognitive capacities of animals is important, because (a) several animal models of human neurodegenerative disease are considered poor representatives of the human equivalent and (b) cognitiv...

    Sebastian D. McBride, A. Jennifer Morton in Experimental Brain Research (2018)

  3. Article

    Erratum to: Chronic Paroxetine Treatment Prevents the Emergence of Abnormal Electroencephalogram Oscillations in Huntington’s Disease Mice

    Sandor Kantor, Janos Varga, Shreya Kulkarni, A. Jennifer Morton in Neurotherapeutics (2017)

  4. Article

    Open Access

    Chronic Paroxetine Treatment Prevents the Emergence of Abnormal Electroencephalogram Oscillations in Huntington’s Disease Mice

    Disturbance of rapid eye movement (REM) sleep appears early in both patients with Huntington’s disease (HD) and mouse models of HD. Selective serotonin reuptake inhibitors are widely prescribed for patients wi...

    Sandor Kantor, Janos Varga, Shreya Kulkarni, A. Jennifer Morton in Neurotherapeutics (2017)

  5. No Access

    Article

    Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington’s disease is not improved by treatment with hypoglycaemic agents

    The R6/2 transgenic mouse model of Huntington’s disease (HD) develops a progressive neurological phenotype that involves severe motor and cognitive dysfunctions. Although not a cardinal sign, diabetes has been...

    Mark J. Hunt, A. Jennifer Morton in Experimental Brain Research (2005)