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    Article

    The metabolism and function of sphingolipids and glycosphingolipids

    Sphingolipids and glycosphingolipids are emerging as major players in many facets of cell physiology and pathophysiology. We now present an overview of sphingolipid biochemistry and physiology, followed by a b...

    S. Lahiri, A. H. Futerman in Cellular and Molecular Life Sciences (2007)

  2. Article

    Open Access

    Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization

    The involvement of ceramide in death receptor-mediated apoptosis has been widely examined with most studies focusing on the role of ceramide generated from sphingomyelin hydrolysis. We now analyze the effect o...

    M Ali, J Fritsch, H Zigdon, Y Pewzner-Jung, S Schütze, A H Futerman in Cell Death & Disease (2013)