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Article

Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization

The involvement of ceramide in death receptor-mediated apoptosis has been widely examined with most studies focusing on the role of ceramide generated from sphingomyelin hydrolysis. We now analyze the effect o...

M Ali, J Fritsch, H Zigdon, Y Pewzner-Jung, S Schütze, A H Futerman in Cell Death & Disease (2013)