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17 Result(s)
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A. Agnoli
Psychiatry
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Article
Botulinum toxin treatment in patients with focal dystonia and hemifacial spasm. A multicenter study of the Italian Movement Disorder Group
In six Centers belonging to the Italian Movement Disorder Study Group, the efficacy of botulinum toxin treatment was evaluated in an open collaborative study in 251 patients with focal dystonia and hemifacial ...
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Article
A multicenter Italian randomised study on early treatment of Parkinson disease: comparison of 1-dopa, 1-deprenyl and dopaminoagonists. Study design and short term results
On the long term Parkinson Disease (PD) treatment is often complicated by the occurrence of motor fluctuations. To find out whether early treatment of PD with levodopa, dopaminoagonists or 1-deprenyl is associ...
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Article
Botulinum A toxin injection in patients with blepharospasm, torticollis and hemifacial spasm
Botulinum A toxin was injected into the affected muscles in 20 patients with blepharospasm, 8 with torticollis and 12 with hemifacial spasm. In all cases blepharospasm and hemifacial spasm was abolished or mar...
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Chapter
Spontane intrazerebrale Hämatome des höheren Lebensalters
In einer Populationsstudie aus den USA, die sich auf 1,5 Mio. Einwohner des Staates Ohio bezog, stieg die Inzidenz der spontanen intrazerebralen Hämatome mit jeder Lebensdekade etwa auf das Doppelte [1]. 80jäh...
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Chapter
Die spontane Subarachnoidalblutung im höheren Lebensalter
Die Fortschritte in der neurochirurgischen Operationstechnik und der Anästhesiologie ermöglichen zunehmend auch die operative Intervention bei alten Patienten mit spontanen Subarachnoidalblutungen (SAB). Gegen...
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Chapter
Welche klinische Relevanz besitzt die arteriosklerotische Leukenzephalopathie (Leuko-Araiosis)?
Die subakute arteriosklerotische Enzephalopathie vom Binswanger-Typ (SAE) ist eine Sonderform der arteriosklerotischen Demenz. Sie beginnt im 5. oder 6. Lebensjahrzehnt mit intellektuellem Abbau, flüchtigen od...
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Chapter and Conference Paper
Subcutaneous lisuride infusion in Parkinson’s disease: clinical results using different modes of administration
The continuous dopaminergic stimulation provided by infusion of dopamine agonist drugs, is a very effective strategy to control ON-OFF fluctuation in Parkinson’s disease. Lisuride is a potent dopamine agonist ...
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Article
Multicenter trial of L-Deprenylin Parkinson disease
A multicenter trial was conducted at 9 Neurology Departements to evaluate the action of L-Deprenyl, a specific monoamine oxidase-B inhibitor, combined with L-Dopa in the treatment of Parkinson disease. In all,...
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Article
Prolactin response as an index of dopaminergic receptor function in Parkinson's disease. Correlation with clinical findings and therapeutic response
Circadian rhythms of prolactin have been evaluated in thirteen untreated parkinsonian patients before and after 15 days of treatment with L-Dopa + carbidopa. The 24th secretory pattern was not significatively ...
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Article
Dopaminergic and non-dopaminergic neurons in substantia nigra: Differential response to bromocriptine
Bromocriptine reduces the spontaneous firing rate of neurons in the pars compacta of the substantia nigra but does not change the electrical activity of the neurons located in the pars reticulata. On the other...
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Book
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Chapter
Introduction
The transfer of a methyl group from a donor to an acceptor compound is a fundamental biochemical process long since known to biologists; the process is involved, for instance, in the metabolism of porphyrins, ...
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Chapter
Results and Possible Developments of the Clinical Use of S-Adenosyl-L-Methionine (SAMe) in Psychiatry
Experimental work on the acute, chronic, and fetal toxicity of SAMe was carried out by Stramentinoli and his colleagues (19). The intravenous LD50 in rats is more than 2000 mg/kg, or the equivalent of 140–150 g i...
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Chapter
S-Adenosyl-L-Methionine and GABA Metabolism in the Brain
Gamma-aminobutryric acid (GABA) (Fig. 1) and S-adenosyl-L-methionine (SAMe) have different and not completely understood roles within the framework of brain tissue metabolism.
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Chapter
SAMe and Histamine
The ralationships between SAMe and histamine are evident on at least one level: namely that SAMe serves as the methyl donor in the methyltransferase system that seems to represent the main catabolic pathway of...
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Chapter
Effect of Acute Hyperammonemia on Metabolism and Cerebral Energy State
The acute effect of hyperammonemia, kept at the level of 0.2 mM by adding ammonium acetate to circulating blood, was evaluated in the isolated dog brain in situ. The interference of the transmethylating system...
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Article
Fehlende Darstellung von Hirngefäßen im Carotisangiogramm infolge intrakranieller Drucksteigerung
In 6 patients, the intracranial vessels were not stained by carotis angiography, although the needle was correctly placed in the arteria carotis communis, and the external carotid, including its branches, were...
