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  1. Article

    Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response

    Effective anticancer treatments often result in the induction of large amounts of tumour cell death. In vivo, such dying tumour cells are a potential source of antigens for T-cell stimulation. Although apoptosis ...

    M H M Melis, K L Simpson, S J Dovedi, A Welman… in Cell Death & Differentiation (2013)

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    Article

    TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB

    Aneurysmal bone cyst (ABC) is an aggressive, pediatric bone tumor characterized by extensive destruction of the surrounding bone. Although first described over 60 years ago, its molecular etiology remains poor...

    Y Ye, L M Pringle, A W Lau, D N Riquelme, H Wang, T Jiang, D Lev, A Welman… in Oncogene (2010)

  3. Article

    Open Access

    Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity

    Overexpression and/or activity of c-Src non-receptor tyrosine kinase is associated with progression of several human epithelial cancers including breast cancer. c-Src activity in ‘pure’ ductal carcinoma in situ (...

    G R Wilson, A Cramer, A Welman, F Knox, R Swindell… in British Journal of Cancer (2006)

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