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Integrating developmental signals: a Hippo in the (path)way

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  1. Article

    Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients

    As a component of the apoptosome, a caspase-activating complex, Apaf-1 plays a central role in the mitochondrial caspase activation pathway of apoptosis. We report here the identification of a novel Apaf-1 int...

    V Piddubnyak, P Rigou, L Michel, J-C Rain, O Geneste… in Cell Death & Differentiation (2007)

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