5 Result(s)
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Article
On the stochastic theory of compartments: I. A single-compartment system
A stochastic model is developed for a compartment with a single time-dependent input, and generalized to include inputs from several sources. With the number of particles of a given molecular species in the co...
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Article
On the stochastic theory of compartments: II. Multi-compartment systems
A stochastic model is developed for a system of interconnected compartments. The generating function of the random variable of any compartment can be constructed from a flow graph involving the expectations of...
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Article
TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses
The multiple isoforms of p73, a member of the p53 family, share the ability to modulate p53 activities but also have unique properties, leading to a complex and poorly understood functional network. In vivo, p73 ...
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Article
Open AccessStromal SLIT2 impacts on pancreatic cancer-associated neural remodeling
Pancreatic ductal adenocarcinoma (PDA) is a critical health issue in the field of cancer, with few therapeutic options. Evidence supports an implication of the intratumoral microenvironment (stroma) on PDA pro...
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Article
TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma
Advances made in pancreatic cancer therapy have been far from sufficient and have allowed only a slight improvement in global survival of patients with pancreatic ductal adenocarcinoma (PDA). Recent progresses...
