10 Result(s)
within
A González
Oncology
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Article
Effect of Paclitaxel-based Hyperthermic Intraperitoneal Chemotherapy (HIPEC) on colonic anastomosis in a rat model
Paclitaxel has been used frequently for Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for ovarian carcinomatosis. Cytoreductive surgery and HIPEC are associated with high rates of morbidity being anastomot...
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Article
Open AccessGalician consensus on management of cardiotoxicity in breast cancer: risk factors, prevention, and early intervention
This Galician consensus statement is a joint oncologists/cardiologists initiative indented to establish basic recommendations on how to prevent and to manage the cardiotoxicity in breast cancer with the aim of...
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Article
A definition for aggressive disease in patients with HER-2 negative metastatic breast cancer: an expert consensus of the Spanish Society of Medical Oncology (SEOM)
To converge on an expert opinion to define aggressive disease in patients with HER2-negative mBC using a modified Delphi methodology.
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Article
Response of Two Barley Cultivars to Increasing Concentrations of Cadmium or Chromium in Soil During the Growing Period
The heavy metal contamination of soils is a serious environmental issue because excessive metal concentrations pose risks to the health of humans, animals, and plants. For this reason, the interest in understa...
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Article
p53 pathway activation by telomere attrition in X-DC primary fibroblasts occurs in the absence of ribosome biogenesis failure and as a consequence of DNA damage
Dyskeratosis congenita (DC) is a rare inherited bone marrow failure syndrome with high clinical heterogeneity. Various mutations have been reported in DC patients, affecting genes that code for components of H...
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Article
BRCA1 and BRCA2 germline mutations in Uruguayan breast and breast–ovarian cancer families. Identification of novel mutations and unclassified variants
The aim of the present study was to analyze BRCA1 and BRCA2 mutations in Uruguayan families with breast and breast/ovarian cancer. Probands from 42 families with at least three cases of female breast cancer (B...
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Article
Open AccessMelatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells
Melatonin reduces the development of breast cancer interfering with oestrogen-signalling pathways, and also inhibits aromatase activity and expression. Our objective was to study the promoters through which me...
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Article
Open AccessInhibitory effects of pharmacological doses of melatonin on aromatase activity and expression in rat glioma cells
Melatonin exerts oncostatic effects on different kinds of neoplasias, especially on oestrogen-dependent tumours. Recently, it has been described that melatonin, on the basis of its antioxidant properties, inhi...
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Chapter and Conference Paper
DISCIR: an architecture for high performance distributed and component-oriented image diagnosis applications
The DISCIR (Distributed Computed Integrated Radiology [1]) is a multi-user, multicomputer, multi-threaded parallel computing software architecture for standard image processing tools, such as 3D segmentation, ...
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Article
All-trans retinoic acid in acute promyelocytic leukemia: Preliminary results in Cuba
Seven patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (ATRA). Five (71.4%) achieved complete remission (CR). Most side effects were transient and well tolerated. Hyperle...
