4 Result(s)

Article

Defining a role for fibroblasts in the persistence of chronic inflammatory joint disease

C Buckley, A Filer, O Haworth, G Parsonage, K Raza… in Arthritis Research & Therapy (2005)

Article

Rheumatoid synovial fibroblasts activate endothelial cells and promote neutrophil recruitment in a flow based multicellular model of the rheumatoid pannus

E Smith, F Lally, A Filer, M Stone, J Shaw, GB Nash… in Arthritis Research & Therapy (2005)

Article

Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

Multiple myeloma (MM), an incurable plasma cell malignancy, requires localisation within the bone marrow. This microenvironment facilitates crucial interactions between the cancer cells and stromal cell types ...

G McNee, K L Eales, W Wei, D S Williams, A Barkhuizen, D B Bartlett, S Essex… in Leukemia (2017)

Article

TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

Adaptive model-based dose-finding designs have demonstrated advantages over traditional rule-based designs but have increased statistical complexity but uptake has been slow especially outside of cancer trials...

M. Cole, C. Yap, C. Buckley, W. F. Ng, I. McInnes, A. Filer, S. Siebert, A. Pratt… in Trials (2021)