29 Result(s)
within
A Cohen
Biomedicine
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Article
Open AccessSignaling changes in the stem cell factor–AKT-S6 pathway in diagnostic AML samples are associated with disease relapse
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Article
An SNP linkage scan identifies significant Crohn's disease loci on chromosomes 13q13.3 and, in Jewish families, on 1p35.2 and 3q29
Inflammatory bowel disease (IBD) is a complex genetic disorder of two major phenotypes, Crohn's disease (CD) and ulcerative colitis (UC), with increased risk in Ashkenazi Jews. Twelve genome-wide linkage scree...
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Article
The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases
The intestinal flora has long been thought to play a role either in initiating or in exacerbating the inflammatory bowel diseases (IBD). Host defenses, such as those mediated by the Toll-like receptors (TLR), ...
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Chapter
Overcoming the inability of the injured mammalian central nervous system axons to grow into their degenerating environment
Spontaneous growth of axons after injury is extremely limited in mammalian central nervous system (CNS). It is now clear, however, that injured CNS axons can elongate, but fail to suitably do so unless their e...
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Article
Analysis and prediction of left ventricular performance under load changes during cardiac catheterization
The applicability of a computer model, which relates the transmural mechanical distribution in the left ventricle (LV) to its global function at different loading conditions, was evaluated in patients with nor...
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Chapter and Conference Paper
Glial Cell Differentiation in Regeneration and Myelination
Spontaneous growth of axons after injury is extremely limited in the mammalian central nervous system (CNS). It is now clear, however, that injured CNS axons can be induced to elongate when provided with a sui...
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Chapter and Conference Paper
Modulation of Glial Cell Response to Injury and CNS Regeneration
Axonal injury initiates a cellular response in the non-neuronal cells surrounding the axons. This response includes proliferation of certain non-neuronal cells and infiltration of scavenger cells such as macro...
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Article
Analysis of rubella virus complement-fixing antigens by polyacrylamide gel electrophoresis
The complement fixing antigens of rubella virus have been found to contain virion envelope but little nucleocapsid polypeptides. They are also shown to be associated with two additional polypeptides of host or...
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Article
Immunological characterisation of the rubella E 1 glycoprotein
Three epitopes have been identified on rubella virion envelope polypeptide E 1 using monoclonal antibodies. Antibodies to two of the epitopes, E 1EP1 and E 1EP2, show both haemagglutination inhibition and neutral...
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Article
Rubella virus haemagglutinin: Association with a single virion glycoprotein
Undenatured rubella virus envelope glycoproteins released by Tweenether and trypsin treatment have been separated by Fast Protein Liquid Chromatography. Red cell adsorption located the haemagglutinin on VPI an...
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Article
Rubella virus RNA: Effect of high multiplicity passage
Evidence for the amplification of defective interfering particles of rubella virus after passage at high multiplicity has been obtained. The process is associated with the production of subgenomic rubella RNA ...
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Chapter
The Actin and Myosin Multigene Families
The Actin and Myosin Multigene Families: a) a study of the accumulation of their RNA transcripts demonstrates different developmental strategies during skeletal muscle formation, b) a genetic analysis of their...
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Article
The role of glycosylation on haemagglutination and immunological reactivity of rubella virus
Treatment of purified rubella virus with mixed glycosidases resulted in loss of haemagglutinating (HA) activity but the capacity to combine with haemagglutination inhibiting (HI) and other antibodies was retai...
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Article
Rubella virion polypeptides: Characterization by polyacrylamide gel electrophoresis, isoelectric focusing and peptide map**
Four polypeptides with molecular weights of 55K, 47K, 45K, and 33K have been resolved by polyacrylamide gel electrophoresis of immune precipitated rubella virus. The 47K and 45K components have similar peptide...
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Article
Effect of 2-mercaptoethanol on the haemagglutinating activity and antigenic properties of rubella virus
Tween-ether treated rubella virus extract treated with 2-mercaptoethanol no longer haemagglutinates and its ability to combine with antibody is reduced although its sedimentation characteristics and the electr...
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Article
Degradation of rubella virus envelope components
Tween-ether treatment of rubella virus, which has no effect on the antigenic and electrophoretic properties of the two envelope glycoproteins, destroys infectivity and enhances haemagglutinating activity. Tryp...
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Article
Breathing ratemeter for neonatal intensive care
A new bit-to-bit ratemeter based on rate multiplication is described. The ratemeter is part of a signal monitoring and processing system used to analyse, respiratory signals of neonates that are characterised ...
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Article
SV 40 induced polypeptides in infected and transformed cells
5 structural (VP) and 3 non-structural (NSVP) SV 40 induced polypeptides which display two kinetic patterns of synthesis are identified in infected cells. NSVP 1 and 2 are ‘early’ functions of which only NSVP ...
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Article
Virion polypeptides and structure of SV 40
Five virion polypeptides, VPI to VPV, have been identified in purified SV40 virus by polyacrylamide gel electrophoresis of which two, VPI and VPII, have been located in the virus capsid. The number of molecula...
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Article
A light emitting diode skin reflectance oximeter
An instrument for monitoring backscattered light from living tissue, in two wavelengths, is described. The backscattered light data is used for thein vivo determination of the blood's relative oxygen saturation. ...
