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  1. Article

    Open Access

    High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections

    The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induc...

    Else Quist-Paulsen, Pål Aukrust, Anne-Marte Bakken Kran in Journal of Neuroinflammation (2018)

  2. No Access

    Article

    Serum B6 vitamers (pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid) and pancreatic cancer risk: two nested case–control studies in Asian populations

    Vitamin B6 is an important enzymatic cofactor in pathways relevant for the development of pancreatic cancer. In order to evaluate vitamin B6 as a preventive factor for pancreatic cancer, a biomarker approach is n...

    Joyce Y. Huang, Lesley M. Butler, Øivind Midttun, Woon-Puay Koh in Cancer Causes & Control (2016)

  3. Article

    Open Access

    Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study

    Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Mea...

    Shu-Chun Chuang, Heiner Boeing, Stein Emil Vollset, Øivind Midttun in Immunity & Ageing (2016)