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374 Result(s)
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Article
Nomogram to predict radicular grooves in maxillary lateral incisors in preoperative orthodontic population
This study aimed to develop and validate a predictive nomogram for diagnosing radicular grooves (RG) in maxillary lateral incisors (MLIs), integrating demographic information, anatomical measurements, and Cone...
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Article
Open AccessNociceptive adenosine A2A receptor on trigeminal nerves orchestrates CGRP release to regulate the progression of oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) associated pain commonly predicts adverse events among patients. This clinical feature indicates the engagement of nociceptors on sensory neurons during the development of m...
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Article
Open AccessExpert consensus on endodontic therapy for patients with systemic conditions
The overall health condition of patients significantly affects the diagnosis, treatment, and prognosis of endodontic diseases. A systemic consideration of the patient’s overall health along with oral condition...
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Open AccessIntegrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC
Metabolic heterogeneity plays a central role in sustaining uncontrolled cancer cell proliferation and sha** the tumor microenvironment (TME), which significantly compromises the clinical outcomes and respons...
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Open AccessA comparative study of microbial changes in dental plaque before and after single- and multiappointment treatments in patients with severe early childhood caries
The status of dental caries is closely related to changes in the oral microbiome. In this study, we compared the diversity and structure of the dental plaque microbiome in children with severe early childhood ...
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Article
Open AccessCone-wedge anchored surgical templates for stackable metal guide: a novel technique
To address the instability in implant surgical guides, this technique proposes an alternative anchoring mechanism in the stackable metal surgical guides utilizing cone-wedge anchors for improved stability.
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Article
Open AccessEfficacy of Danzhixiaoyao tablets combined with methylcobalamin tablets in the treatment of burning mouth syndrome: an open-label, randomized controlled trial
This randomized controlled trial compared the efficacy and tolerability of danzhixiaoyao pills in the accurate treatment of patients with burning mouth syndrome (BMS).
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Open AccessOral frailty: a concept analysis
Oral frailty has become a worldwide problem among older adults. Although researchers have conducted various studies on oral frailty, its definition remains controversial.
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Article
Open AccessMalignant transformation of white sponge nevus: a case report of a novel keratin 4 mutation
White Sponge Nevus (WSN) is traditionally considered a benign genetic disorder affecting the oral mucosa, primarily caused by pathogenic mutations in keratin 4 (KRT4) or keratin 13 (KRT13). Despite its benign nat...
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Article
Feasibility study of a novel digital template-guided flapless extraction for maxillary palatal impacted teeth
With the increasing maturity of 3D printing technology, the application of digital guide template in the extraction of impacted teeth has become more sophisticated. However, for maxillary palatal deeply impact...
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Article
Open AccessHuman dental pulp stem cells mitigate the neuropathology and cognitive decline via AKT-GSK3β-Nrf2 pathways in Alzheimer’s disease
Oxidative stress is increasingly recognized as a major contributor to the pathophysiology of Alzheimer’s disease (AD), particularly in the early stages of the disease. The multiplicity advantages of stem cell ...
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Article
Open AccessSimultaneous detection of dental caries and fissure sealant in intraoral photos by deep learning: a pilot study
Deep learning, as an artificial intelligence method has been proved to be powerful in analyzing images. The purpose of this study is to construct a deep learning-based model (ToothNet) for the simultaneous det...
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Article
Open AccessCorrection to: Computational fluid dynamics investigation on the irrigation of a real root canal with a side-vented needle
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Open AccessFull life cycle changes of low impacted mandibular third molar associated cystic lesions and adjacent tooth root resorption: a retrospective study
Low impacted third molars are usually asymptomatic and are often found by X-ray examination. The removal of asymptomatic low impacted third molars is one of the most controversial clinical issues in oral and m...
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Article
Identification of a novel de novo mutation in SOX4 for syndromic tooth agenesis
Coffin-Siris Syndrome (CSS) is a congenital disorder characterized by delayed growth, dysmorphic facial features, hypoplastic nails and phalanges of the fifth digit, and dental abnormalities. Tooth agenesis ha...
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Article
Open AccessMulti-omics analysis of immune-related microbiome and prognostic model in head and neck squamous cell carcinoma
The aim of our study is to explore the transcriptional and microbial characteristics of head and neck cancer’s immune phenotypes using a multi-omics approach.
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Open AccessComparison of temporomandibular joints in relation to ages and vertical facial types in skeletal class II female patients: a multiple-cross-sectional study
The temporomandibular joint (TMJ) is closely related to the dynamic balance and stability of mandibular function and orthodontic treatment. Skeletal class II female patients are thought to be at high risk for ...
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Article
Open AccessExpert consensus on pediatric orthodontic therapies of malocclusions in children
Malocclusion, identified by the World Health Organization (WHO) as one of three major oral diseases, profoundly impacts the dental-maxillofacial functions, facial esthetics, and long-term development of ~260 m...
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Article
Open AccessSingle cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification
Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There is mounting evidence that tumor-infiltrating B cells (TIL-Bs...
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Article
Open AccessMean platelet volume is associated with periodontitis: a cross-sectional study
It is uncertain if mean platelet volume and periodontitis are related. The objective of this study was to examine the association between levels of mean platelet volume and moderate/severe periodontitis in adu...