4,949 Result(s)
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**yuan Liu
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Article
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a central focus of immunotherapy to treat cancer. When CD8+ T cells specifically recognize antige...
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A meaningful image encryption method based on dynamic update pixel diffusion and 2D hyperchaotic map
This paper reports a meaningful image encryption method (SHHM-IEM) based on a novel 2D hyperchaotic map (2D-SHHM) derived from classical Sine and Henon maps, which can be applied to protect global and local in...
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Open AccessGlobal well-posedness of the 2D nonlinear Schrödinger equation with multiplicative spatial white noise on the full space
We consider the nonlinear Schrödinger equation with multiplicative spatial white noise and an arbitrary polynomial nonlinearity on the two-dimensional full space domain. We prove global well-posedness by using...
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Open AccessIPSC-NSCs-derived exosomal let-7b-5p improves motor function after spinal cord Injury by modulating microglial/macrophage pyroptosis
Following spinal cord injury (SCI), the inflammatory storm initiated by microglia/macrophages poses a significant impediment to the recovery process. Exosomes play a crucial role in the transport of miRNAs, fa...
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Open AccessHigh positive predictive value of CNVs detected by clinical exome sequencing in suspected genetic diseases
Genetic disorders often manifest as abnormal fetal or childhood development. Copy number variations (CNVs) represent a significant genetic mechanism underlying such disorders. Despite their importance, the eff...
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Delineation of the phenotypes and genotypes of PIK3CA-related overgrowth spectrum in East asians
PIK3CA-related overgrowth spectrum (PROS) is an umbrella term to describe a diverse range of developmental disorders. Research to date has predominantly emerged from Europe and North America, resulting in a notab...
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Ethnic-specific genetic susceptibility loci for endometriosis in Taiwanese-Han population: a genome-wide association study
Endometriosis is a common gynecological disorder affecting around 10% of reproductive-age women. Although many hypotheses were proposed, genetic alteration has been considered as one of the key factors promoti...
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Mesenchymal Stem Cell-Loaded Hydrogel Improves Surgical Treatment for Chronic Cerebral Ischemia
Chronic cerebral ischemia (CCI) results in a prolonged insufficient blood supply to the brain tissue, leading to impaired neuronal function and subsequent impairment of cognitive and motor abilities. Our previ...
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Open AccessDietary restriction promote sperm remodeling in aged roosters based on transcriptome analysis
The breeder rooster has played a pivotal role in poultry production by providing high-quality semen. Typically, fertility peaks between 30 and 40 weeks of age and then declines rapidly from 45 to 55 weeks of a...
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Article
Open AccessMeasurement of the distance between tumor micro-foci and gross tumor in rectal cancer pathological specimens: implication on margin distance of clinical target volume treated with high-dose radiotherapy for rectal cancer
To measure the micro-foci distance away from gross tumor and to provide reference to create the clinical target volume (CTV) margin for boost radiotherapy in rectal adenocarcinoma.
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Open AccessUltrastable and efficient slight-interlayer-displacement 2D Dion-Jacobson perovskite solar cells
Stability has been a long-standing concern for solution-processed perovskite photovoltaics and their practical applications. However, stable perovskite materials for photovoltaic remain insufficient to date. H...
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Open AccessBiotin-modified mesoporous silica nanoparticles as a delivery system for quercetin and gallic acid for bacterial biofilm eradication
The effective management of biofilm-associated infections remains a pressing concern in clinical practice, necessitating the development of efficient eradication strategies. This study introduces biotin-modifi...
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Article
A Stable Copper-based Metal-Azolate Framework for Efficient Electroreduction of CO2 to C2+ Products
Driven by renewable or excess electrical energy, electrochemical CO2 reduction reaction (eCO2RR) represents a promising carbon-neutral approach to generating valuable low-carbon fuels by consuming CO2 and H2O. C2...
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Open AccessThe pathogenesis mechanism and potential clinical value of lncRNA in gliomas
Glioma is the most common malignant tumor in the central nervous system, and its unique pathogenesis often leads to poor treatment outcomes and prognosis. In 2021, the World Health Organization (WHO) divided g...
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Open AccessStable peptide-assembled nanozyme mimicking dual antifungal actions
Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic candidates against antimicrobial resistance but suffer from low efficiency and poor stability. Here, we develop peptide nan...
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Article
Torque Improvement and Analysis of a Bearingless Switched Reluctance Motor Under Efficient Levitation Excitation
In a bearingless switched reluctance motor (BSRM), there is a conflict between the output regions of effective radial force and positive torque. So a compromise between radial force and torque is usually appli...
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Open AccessEffects of low-intensity pulsed ultrasound on the microorganisms of expressed prostatic secretion in patients with IIIB prostatitis
To detect and analyze the changes of microorganisms in expressed prostatic secretion (EPS) of patients with IIIB prostatitis before and after low-intensity pulsed ultrasound (LIPUS) treatment, and to explore t...
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Open AccessCorrelates of oral pre-exposure prophylaxis cessation among men who have sex with men in China: implications from a nationally quantitative and qualitative study
Several studies have demonstrated the population-level effectiveness of oral PrEP in reducing the risk of HIV infection. However, oral PrEP utilization among MSM in China remains below 1%. While existing liter...
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Author Correction: Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial
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Open AccessExperimental study on seismic characteristics of slope supported by long-short composite anti-slide piles
In this study, a shaking table test was conducted on long-short composite anti-slide piles, the development process and dynamic response of cracks in a pile-supported slope were observed, and the failure mecha...
