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2,062 Result(s)
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Article
Annealing-induced gradient nanostructured FeCrAlTiMo high-entropy alloy coatings with significantly enhanced wear resistance
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Amino Acid-Modified Porous Carbon Foams Derived from Wheat Powder with Enhanced Adsorption Performance for VOCs
Porous carbon foam (PCF), known for its high surface area and abundant functional groups, is considered to exhibit superior adsorption capacity and wide applicability for gases. Wheat, being a widely cultivate...
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Article
Open AccessRunning safety assessment method of trains under seismic conditions based on the derailment risk domain
The accurate assessment of running safety during earthquakes is of significant importance for ensuring the safety of railway lines. Currently, assessment methods based on a single index suffer from issues such...
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Open AccessA near complete genome assembly of the East Friesian sheep genome
Advancements in sequencing have enabled the assembly of numerous sheep genomes, significantly advancing our understanding of the link between genetic variation and phenotypic traits. However, the genome of Eas...
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Open AccessPrecipitation of secondary Laves phases and its effect on notch sensitivity
The precipitation of secondary Laves phases and its effect on notch sensitivity are systematically studied in Thermo-Span alloy. The results show that the precipitation peak temperature of secondary Laves phas...
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Article
Open AccessEnd of the world brane meets \( T\overline{T} \)
End of the world branes in AdS have been recently used to study problems deeply connected to quantum gravity, such as black hole evaporation and holographic cosmology. With non-critical tension and Neumann bou...
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Article
Open AccessRelationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia
Increasing evidence suggested that immune abnormalities involved in the pathophysiology of schizophrenia. However, the relationship between immunity and clinical features has not been clarified. The aim of thi...
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Article
Effect of La2O3 on Microstructure and Mechanical Properties of Mg–3Y Alloy
The preparation of high-performance rare earth magnesium (Mg–RE) alloy still heavily relies on expensive master alloy as a critical raw material. In order to address this issue, a series of Mg–3Y–xLa2O3 (x = 0, 0...
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Article
Research on die-less spinning by spherical roller of different radius
Die-less spinning is developed because of its advantages of low cost and high flexibility. The spherical roller has not been commonly used in the die-less spinning process. In previous studies, the sizes of th...
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Effect of Artificial Cooling Extrusion on Microstructure and Mechanical Properties of Mg–Zn–Y Alloys
Microstructure and mechanical properties of Mg–Zn–Y alloys with different Zn/Y atomic ratios with or without artificial cooling (AC) extrusion were systematically investigated in this work. The results show th...
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Article
Optimal Planning of Multiple Geosynchronous Spacecraft Flyby Inspection Mission with Multiple Servicing Space Robots
The optimization of multiple geosynchronous spacecraft inspection problem (MGSIP) with multiple servicing space robots (SSRs) is studied in this paper. A new economical maneuver strategy for visiting multiple ...
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Article
Small molecule–engineered nanoassembly for lipid peroxidation–amplified photodynamic therapy
Photodynamic therapy (PDT), extensively explored as a non-invasive and spatio-temporal therapeutic modality for cancer treatment, encounters challenges related to the brief half-life and limited diffusion rang...
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Immunosuppressive regulatory cells in cancer immunotherapy: restrain or modulate?
Immunosuppressive regulatory cells (IRCs) play important roles in negatively regulating immune response, and are mainly divided into myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs). Lar...
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Open AccessNonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data
The atherogenic index of plasma (AIP) is closely associated with the onset of diabetes, with obesity being a significant risk factor for type 2 diabetes mellitus (T2DM). However, the association between the AI...
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Open AccessThe global distribution of the macrolide esterase EstX from the alpha/beta hydrolase superfamily
Macrolide antibiotics, pivotal in clinical therapeutics, are confronting resistance challenges mediated by enzymes like macrolide esterases, which are classified into Ere-type and the less studied Est-type. In...
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Interface-driven structural evolution on diltiazem as novel uPAR inhibitors: from in silico design to in vitro evaluation
The urokinase-type plasminogen activator receptor (uPAR) emerges as a key target for anti-metastasis owing to its pivotal role in facilitating the invasive and migratory processes of cancer cells. Recently, we...
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Open AccessTherapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway
The microglia-mediated neuroinflammation have been shown to play a crucial role in the ocular pathological angiogenesis process, but specific immunotherapies for neovascular ocular diseases are still lacking. ...
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Article
Cystathionine γ-lyase-derived H2S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase
Thymic egress is a crucial process for thymocyte maturation, strictly regulated by sphingosine-1-phosphate lyase (S1PL). Recently, cystathionine γ-lyase (CSE), one of the enzymes producing hydrogen sulfide (H2S),...
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Article
Rankin–Cohen brackets of Hilbert Hecke eigenforms
Over any fixed totally real number field with narrow class number one, we prove that the Rankin–Cohen bracket of two Hecke eigenforms for the Hilbert modular group can only be a Hecke eigenform for dimension r...
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Article
Generalized Out-of-Distribution Detection: A Survey
Out-of-distribution (OOD) detection is critical to ensuring the reliability and safety of machine learning systems. For instance, in autonomous driving, we would like the driving system to issue an alert and h...