20 Result(s)
within
Medicine & Public Health
Infectious Diseases
**yan Xu
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Article
Open AccessPersonalized prediction of mortality in patients with acute ischemic stroke using explainable artificial intelligence
Research into the acute kidney disease (AKD) after acute ischemic stroke (AIS) is rare, and how clinical features influence its prognosis remain unknown. We aim to employ interpretable machine learning (ML) mo...
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Article
The Chinese keratoconus (CKC) cohort study
The Chinese keratoconus (CKC) cohort study is a population-based longitudinal prospective cohort study in the Chinese population involving a clinical database and biobanks. This ongoing study focuses on the pr...
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Article
Open AccessEfficacy and safety of oral ibrexafungerp in Chinese patients with vulvovaginal candidiasis: a phase III, randomized, double-blind study
To evaluate the efficacy and safety of oral ibrexafungerp (HS-10366) versus placebo in Chinese patients with vulvovaginal candidiasis (VVC).
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Article
Open AccessClinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study
Healthcare-associated Gram-negative bacterial meningitis is a substantial clinical issue with poor outcomes, especially for neurosurgical patients. Here, we aimed to study the characteristics and treatment opt...
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Article
Open AccessCorrection: Exploring the association between triglyceride-glucose index and thyroid function
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Article
Open AccessExploring the association between triglyceride-glucose index and thyroid function
Thyroid dysfunction is associated with abnormal glucose-insulin homeostasis, and the triglyceride-glucose (TyG) index has been recommended as a convenient surrogate of insulin resistance (IR). This study aimed...
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Article
Open AccessHexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway
Hexarelin exhibits significant protection against organ injury in models of ischemia/reperfusion (I/R)-induced injury (IRI). Nevertheless, the impact of Hexarelin on acute kidney injury (AKI) and its underlyin...
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Open AccessHospitalized patients received furosemide undergoing acute kidney injury: the risk and prediction tool
Furosemide, a frequently prescribed diuretic for managing congestive heart failure and edema, remains a topic of debate regarding its potential risk of inducing acute kidney injury (AKI) in patients. Consequen...
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Article
Open AccessThe relationship between aspirin consumption and hepatocellular carcinoma: a systematic review and meta-analysis
Recent studies have shown that aspirin consumption may reduce the risk of hepatocellular carcinoma (HCC), but their correlation is still not fully understood. This meta-analysis aimed to investigate the correl...
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Article
Open AccessThe prevalence of soil transmitted helminths and its influential factors in Shandong Province, China: an analysis of surveillance data from 2016 to 2020
Soil-transmitted helminths (STHs) were previously endemic in Shandong Province, China. This study aimed to analyze the STHs prevalence trend and the natural, social, and human cognitive and behavioural factors...
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Article
Open AccessObesity difference on association blood malondialdehyde level and diastolic hypertension in the elderly population: a cross-sectional analysis
Although increased production of malondialdehyde (MDA), an end product of lipid oxidation caused by reactive oxygen species (ROS), has been found be elevated in hypertensive population, whether MDA contributed...
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Article
Open AccessPediatric lumbar disc herniation: a report of two cases and review of the literature
Lumbar disc herniation (LDH) is not a common condition in children. Most reports on pediatric LDH concern the outcomes of surgeries performed in children in whom nonsurgical treatment failed while the outcome ...
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Article
Open AccessSerum CA-125 for the diagnosis of pulmonary tuberculosis: a systematic review and meta-analysis
Pulmonary tuberculosis (PTB) remains the world’s deadliest infectious killer. Serum CA-125 test are useful in the diagnosis of PTB. Although studies on the relation between CA-125 and PTB have been reported, t...
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Article
Open AccessClinical characteristics of children with airway malacia complicated by pneumonia
Airway malacia is an important cause of noisy breathing, recurrent wheezing and respiratory infections, chronic coughing, and episodes of respiratory distress in young children. As the clinical manifestations ...
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Open AccessCharacterization of Salmonella serotypes prevalent in asymptomatic people and patients
Infection with Salmonella enterica usually results in diarrhea, fever, and abdominal cramps, but some people become asymptomatic or chronic carrier as a source of infection for others. This study aimed to analyze...
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Article
Open AccessClinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases
Klebsiella pneumoniae is a primary pathogen of pyogenic liver abscess (PLA). However, little data are available on combination with sepsis. In this study, we aimed to evaluate the clinical characteristics and pro...
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Article
Open AccessRisk factors for secondary hemophagocytic lymphohistiocytosis in severe coronavirus disease 2019 adult patients
Secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening hyperinflammatory event and a fatal complication of viral infections. Whether sHLH may also be observed in patients with a cytokine sto...
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Article
Open AccessA rare case of adult herpes simplex encephalitis complicated with rhabdomyolysis
Compelling evidence indicates that status epilepticus is a prevalent cause of rhabdomyolysis. However, cases of rhabdomyolysis induced by a single seizure accompanied by viral encephalitis are rarely reported....
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Article
Open AccessLncRNA NEAT1 promotes nucleus pulposus cell matrix degradation through regulating Nrf2/ARE axis
This study aimed to assess the role and mechanism of lncRNA NEAT1 in intervertebral disc degeneration (IVD).
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Article
Open AccessA COVID-19 case report from asymptomatic contact: implication for contact isolation and incubation management
As of 2 March, 2020, at least 80 151 coronavirus disease 2019 (COVID-19) cases were reported in China. Most of the patients had a history of visiting Hubei Province or contacting with people who had ever staye...
