445 Result(s)
within
**yan Xu
Life Sciences
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Article
Provincial distribution of three HIV-1 resistant polymorphisms (CCR5-Δ32, CCR2-64I, and SDF1-3′ A) in China
CCR5-Δ32, CCR2-64I, mutants in two chemokine receptors and SDF1-3′A, mutant in a ligand gene, can delay AIDS pathogenesis. The distribution of the three polymorphic loci was studied in 1 046 DNA samples from 2...
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Article
Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1
Sphingosylphosphorylcholine (SPC) is a bioactive lipid that acts as an intracellular and extracellular signalling molecule in numerous biological processes. Many of the cellular actions of SPC are believed to ...
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Chapter
CCT mRNA and CREB Phosphorylation Up Regulated by Peptide ZNC(C)PR in Rat Hippocampus
CTP: Phosphocholine cytidylyltransferase (CCT) is a key enzyme in in vivo phospholipid synthesis, which catalyzes the formation of CDP-choline [1,2]. CCT may play an important role in the pathogenesis of neurodeg...
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Article
High-throughput sequence identification of gene coding variants within alcohol-related QTLs
Low initial response to alcohol has been shown to be among the best predictors of development of alcoholism. A similar phenotypic measure, difference in initial sensitivity to ethanol, has been used for the ge...
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Chapter
Purification of Glucose-6-Phosphate Dehydrogenase from Baker’s Yeast in Aqueous Two-Phase Systems with Free Triazine Dyes as Affinity Ligands
To improve the selectivity of glucose-6-phosphate dehydrogenase (G6PDH) extraction by an aqueous two-phase system, a simple and inexpensive affinity aqueous two-phase system using unbound reactive triazine dye...
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Article
Research progress on production of podophyllotoxin from Sinopodophyllum hexandrum
Podophyllotoxin is isolated mainly from the rhizomes of Podophyllum plants, and serves as the main precursor for synthesis of anticancer drugs, such as VP-16 and VM-26. VP-16 and VM-26 are used for curing lung ca...
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Article
High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa
Whole cells of Candida rugosa catalyzed the conversion of (R)-2-octanol from the corresponding racemate with the optical purity of 97% e.e. and yield of 92% in 10 h. The product was formed through a stereoinvers...
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Article
In vivo imaging platform for tracking immunotherapeutic cells
Cellular therapeutics show great promise for the treatment of disease, but few noninvasive techniques exist for monitoring the cells after administration. Here we present a magnetic resonance imaging (MRI) tec...
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Article
Open AccessComparisons of methods for linkage analysis and haplotype reconstruction using extended pedigree data
We compare and contrast the performance of SIMPLE, a Monte Carlo based software, with that of several other methods for linkage and haplotype analyses, focusing on the simulated data from the New York City pop...
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Article
Open AccessEffects of population structure on genetic association studies
Population-based case-control association is a promising approach for unravelling the genetic basis of complex diseases. One potential problem of this approach is the presence of population structure in the sa...
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Article
Blocking of N-acetylglucosaminyltransferase V induces cellular endoplasmic reticulum stress in human hepatocarcinoma 7721 cells
N-acetylglucosaminyltransferase V (GnT-V) is an important tumorigenesis and metastasis-associated enzyme. To study its biofunction, the GnT-V stably suppressed cell line (GnT-V-AS/7721) was constructed from 77...
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Chapter and Conference Paper
Novel Blue- and Red-Shifted Internally Quenched Fluorogenic Substrates for Continuous Monitoring of SARS-CoV 3CLpro
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Article
Open AccessUpregulation of a tonoplast-localized cytochrome P450 during petal senescence in Petunia inflata
Gene expression in Petunia inflata petals undergoes major changes following compatible pollination. Severe flower wilting occurs reproducibly within 36 hours, providing an excellent model for investigation of pet...
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Article
Plant regeneration from leaf explants of Rhodiola fastigiata
An efficient plant regeneration protocol for rapidly propagating Rhodiola fastigiata (Hk. f. et Thoms.) S.H.FU, a traditional Chinese medicinal plant, was developed. Shoot organogenesis occurred from the leaf exp...
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Article
Anti-Prelog Reduction of Prochiral Carbonyl Compounds by Oenococcus oeni in a Biphasic System
An aqueous-organic biphasic system was established and used with whole cells of Oenococcus oeni to reduce 2-octanone to (R)-2-octanol. The conversion reached 99% when the Tris/borate buffer was increased from 50 ...
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Article
Photochemical determination of different DNA structures
The various conformations of DNA are thought to have important biological roles. Investigation of the local DNA conformational changes associated with biological events is therefore essential to an understandi...
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Article
Exogenous GA3 overcomes bud deterioration in tulip (Tulipa gesneriana L.) bulbs during dry storage by promoting endogenous IAA activity in the internodes
Endogenous free IAA was examined with an immunohistochemical method for its involvement in the reduction of bud deterioration after GA3 was injected into the bulbs. We found that tulip bulbs stored at 20°C consta...
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Article
A major QTL associated with cold tolerance at seedling stage in rice (Oryza sativa L.)
Chilling injury is one of the most important limiting factors affecting rice production in temperate and high-elevation areas. In this study, 146 microsatellite markers were employed to identify quantitative t...
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Article
Open AccessGene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells
The signal transducer and activator of transcription 3 (STAT3) mediates gene expression in response to numerous growth factors and cytokines, playing an important role in many cellular processes. To better und...
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Article
Cloning and expression of the gene encoding (R)-specific carbonyl reductase from Candida parapsilosis CCTCC M203011
The gene which encodes (R)-specific carbonyl reductase (rCR) from Candida parapsilosis CCTCC M203011 was cloned, sequenced and compared with genes from the GenBank. The results indicated that rCR gene was 1011 bp...
