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  1. Article

    Numerical simulation of microstructure and microporosity morphology in directional solidification of aluminum-copper alloys: Effect of copper content and withdrawal rate

    Microporosity formed in the solidification process of Al alloys is detrimental to the alloy properties. A two-dimensional cellular automaton (CA) model was developed to simulate the microstructure and micropor...

    Wei Yuan, Hai-dong Zhao, Xu Shen, Chun Zou, Yuan Liu, Qing-yan Xu in China Foundry (2024)

  2. Article

    Open Access

    The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy

    Toxoplasma gondii infection causes adverse pregnancy outcomes by affecting the expression of immunotolerant molecules in decidual immune cells. Galectin-9 (Gal-9) is widely expressed in decidual macrophages (dMφ)...

    **ao Wang, Shuyan Wang, **aoyan Xu, Yuzhu Jiang, Liqin Ren in Parasites & Vectors (2024)

  3. Article

    Open Access

    Advanced enhancement technique for infrared images of wind turbine blades utilizing adaptive difference multi-scale top-hat transformation

    Enhancing infrared images is essential for detecting wind turbine blades using infrared technology. This paper introduces an Infrared Image Enhancement Method based on Adaptive Iterative Cutoff Threshold Diffe...

    Yinchao He, Shuang Kang, Wenwen Li, Hongyan Xu, Sen Liu in Scientific Reports (2024)

  4. Article

    Open Access

    Correction to: The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy

    Wenxin Lu, Guangyu Wu, **anyuan Miao, **gyu Ma in Cancer Immunology, Immunotherapy (2024)

  5. Article

    Open Access

    Molecular alterations and prognosis of breast cancer with cutaneous metastasis

    Cutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment and poor prognosis. A better understanding of the molecular alterations involved ...

    Yan Xu, Li Ding, Chao Li, Bin Hua, Sha Wang, Junli Zhang in Diagnostic Pathology (2024)

  6. No Access

    Article

    A DEM upscaling method with integrating valley lines based on HASM

    A new digital elevation model (DEM) upscaling method based on high accuracy surface modeling (HASM) is proposed by combining the elevation information of DEM and the valley lines extracted from DEM with differ...

    Mingwei Zhao, **aoxiao Ju, Na Zhao, Chun Wang, Yan Xu in Frontiers of Earth Science (2024)

  7. Article

    Open Access

    Constructing diagnostic signature of serum microRNAs using machine learning for early pan-cancer detection

    Cancer is a major public health concern and the second leading cause of death worldwide. Various studies have reported the use of serum microRNAs (miRNAs) as non-invasive biomarkers for cancer detection. Howev...

    Yuyan Xu, Wei Liao, Huanwei Chen, Mingxin Pan in Discover Oncology (2024)

  8. No Access

    Article

    Reaction Mechanism of Actin ATP Hydrolysis Studied by QM/MM Calculations

    Actin fibers are an important part of the cytoskeleton, providing vital support for the plasma membrane. This function is driven by its ATPase (ATP: adenosine triphosphate) activity, i.e., ATP+H2O→ADP+Pi. This se...

    Yiwen Wang, Lirui Lin, Li-Yan Xu, En-Min Li in Chemical Research in Chinese Universities (2024)

  9. No Access

    Article

    Event-Driven Heterogeneous Network for Video Deraining

    Restoring clear frames from rainy videos poses a significant challenge due to the swift motion of rain streaks. Traditional frame-based visual sensors, which record dense scene content synchronously, struggle ...

    Xueyang Fu, Chengzhi Cao, Senyan Xu in International Journal of Computer Vision (2024)

  10. No Access

    Article

    Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses

    Major depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel...

    **aoyu Zhou, Cheng Zhao, Haiyan Xu, Yixiang Xu, Li Zhan in Nature Chemical Biology (2024)

  11. No Access

    Article

    The clinical significance and prognostic value of serum beta-2 microglobulin in adult lymphoma-associated hemophagocytic lymphohistiocytosis: a multicenter analysis of 326 patients

    To investigate the prognostic impact of serum beta-2 microglobulin (B2M) in adult lymphoma-associated hemophagocytic lymphohistiocytosis (HLH). The clinical and laboratory characteristics of 326 adult patients...

    Ze **, Yi Miao, Jie Zhang, **g Zhang, Chunling Wang, Xuzhang Lu in Annals of Hematology (2024)

  12. No Access

    Article

    Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice

    Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It represents a significant detriment to female fertility. However, ...

    Chengcheng Song, Yingying Qin, Yan Li, Bingyi Yang, Ting Guo in Science China Life Sciences (2024)

  13. Article

    Open Access

    Evaluating the efficacy of laparoscopic radical antegrade modular pancreatosplenectomy in selected early-stage left-sided pancreatic cancer: a propensity score matching study

    Laparoscopic radical pancreatectomy is safe and beneficial for recectable pancreatic cancer, but the extent of resection for early-stage tumors remains controversial.

    Zheng Li, Wenyan Xu, Ting Wang, Borui Li, Chen Chen, Yihua Shi in Surgical Endoscopy (2024)

  14. No Access

    Article

    Integrative analyses of transcriptome, microRNA-seq and metabolome reveal insights into exogenous melatonin-mediated salt tolerance during seed germination of maize

    Melatonin is an important phytohormone influencing plant growth and defense responses. However, the mechanism mediating the regulatory effects of melatonin on the salt tolerance of germinating maize seeds rema...

    Shuhui Xu, Shuting Wang, Zhichao Wang, Yue Lu, Tianyun Tao in Plant Growth Regulation (2024)

  15. No Access

    Article

    Natural Microcellulose Fibers as Intercalants of Graphitic Cathodes for High-Performance Lithium–Sulfur Batteries

    A free-standing highly porous graphitic scaffold of S was fabricated via intercalating microcellulose fibers into graphene oxide (GO) nanosheets, followed by high-temperature carbonization. The abundant porous...

    **sheng Rui, Ruyan Xu, **nke Yan, Yihong Liu in Journal of Electronic Materials (2024)

  16. No Access

    Article

    Liquid-phase hydrogenation of dimethyl maleate to 1,4-butanediol over a sorbitol-modified Cu@C/ZnO catalyst

    With the growing global demand for biodegradable plastics, the hydrogenation of dimethyl maleate (DMM) to produce 1,4-butanediol (BDO), raw materials for poly(butylene succinate), has become one of the hot spo...

    Lu Wang, Mooeez ur Rehman, Yong Jiang, Fan Sun in Research on Chemical Intermediates (2024)

  17. No Access

    Article

    Relationship between changes in late-life blood pressure and the risk of frailty and mortality among older population in China: a cohort study based on CLHLS

    The evidence regarding the effects of blood pressure changes on older individuals remains inconclusive, and the impact of frailty throughout the life course is not known. We investigated the associations of di...

    Yana Chen, Yanfang Wang, Yan Xu, Shunyao Shi, Zhong Tian in Hypertension Research (2024)

  18. No Access

    Article

    The resistance to short-term dehydration in the bdelloid rotifer Rotaria rotatoria from different climate regions

    Exceptional resistance to dehydration allows species of bdelloid rotifers to tolerate desiccation stress in unpredictable habitats. The roles of exogenous and endogenous factors in resistance to short-term deh...

    **anling **ang, Chan Wang, Lin Huang, Lingyun Zhu, **gyan Xu, **nli Wen in Hydrobiologia (2024)

  19. No Access

    Article

    Legionella effector LnaB is a phosphoryl AMPylase that impairs phosphosignalling

    AMPylation is a post-translational modification in which AMP is added to the amino acid side chains of proteins1,2. Here we show that, with ATP as the ligand and actin as the host activator, the effector protein ...

    Ting Wang, **aonan Song, Jiaxing Tan, Wei **an, **ngtong Zhou, Mingru Yu in Nature (2024)

  20. No Access

    Article

    Improvement of impact properties of Al–Si–Mg alloy via solution treatment and joint modification with Sr and La

    An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented, where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly employed. The samples were sol...

    **ong-Ling Zheng, Shao-**ang Li, Jia-Le Ma, Qing-Yan Xu, Hai-Dong Zhao in Rare Metals (2024)

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