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3,091 Result(s)
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Article
Numerical simulation of microstructure and microporosity morphology in directional solidification of aluminum-copper alloys: Effect of copper content and withdrawal rate
Microporosity formed in the solidification process of Al alloys is detrimental to the alloy properties. A two-dimensional cellular automaton (CA) model was developed to simulate the microstructure and micropor...
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Open AccessThe effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy
Toxoplasma gondii infection causes adverse pregnancy outcomes by affecting the expression of immunotolerant molecules in decidual immune cells. Galectin-9 (Gal-9) is widely expressed in decidual macrophages (dMφ)...
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Open AccessAdvanced enhancement technique for infrared images of wind turbine blades utilizing adaptive difference multi-scale top-hat transformation
Enhancing infrared images is essential for detecting wind turbine blades using infrared technology. This paper introduces an Infrared Image Enhancement Method based on Adaptive Iterative Cutoff Threshold Diffe...
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Open AccessCorrection to: The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy
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Article
Open AccessMolecular alterations and prognosis of breast cancer with cutaneous metastasis
Cutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment and poor prognosis. A better understanding of the molecular alterations involved ...
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A DEM upscaling method with integrating valley lines based on HASM
A new digital elevation model (DEM) upscaling method based on high accuracy surface modeling (HASM) is proposed by combining the elevation information of DEM and the valley lines extracted from DEM with differ...
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Open AccessConstructing diagnostic signature of serum microRNAs using machine learning for early pan-cancer detection
Cancer is a major public health concern and the second leading cause of death worldwide. Various studies have reported the use of serum microRNAs (miRNAs) as non-invasive biomarkers for cancer detection. Howev...
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Reaction Mechanism of Actin ATP Hydrolysis Studied by QM/MM Calculations
Actin fibers are an important part of the cytoskeleton, providing vital support for the plasma membrane. This function is driven by its ATPase (ATP: adenosine triphosphate) activity, i.e., ATP+H2O→ADP+Pi. This se...
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Article
Event-Driven Heterogeneous Network for Video Deraining
Restoring clear frames from rainy videos poses a significant challenge due to the swift motion of rain streaks. Traditional frame-based visual sensors, which record dense scene content synchronously, struggle ...
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Article
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
Major depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel...
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Article
The clinical significance and prognostic value of serum beta-2 microglobulin in adult lymphoma-associated hemophagocytic lymphohistiocytosis: a multicenter analysis of 326 patients
To investigate the prognostic impact of serum beta-2 microglobulin (B2M) in adult lymphoma-associated hemophagocytic lymphohistiocytosis (HLH). The clinical and laboratory characteristics of 326 adult patients...
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Article
Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It represents a significant detriment to female fertility. However, ...
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Open AccessEvaluating the efficacy of laparoscopic radical antegrade modular pancreatosplenectomy in selected early-stage left-sided pancreatic cancer: a propensity score matching study
Laparoscopic radical pancreatectomy is safe and beneficial for recectable pancreatic cancer, but the extent of resection for early-stage tumors remains controversial.
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Article
Integrative analyses of transcriptome, microRNA-seq and metabolome reveal insights into exogenous melatonin-mediated salt tolerance during seed germination of maize
Melatonin is an important phytohormone influencing plant growth and defense responses. However, the mechanism mediating the regulatory effects of melatonin on the salt tolerance of germinating maize seeds rema...
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Article
Natural Microcellulose Fibers as Intercalants of Graphitic Cathodes for High-Performance Lithium–Sulfur Batteries
A free-standing highly porous graphitic scaffold of S was fabricated via intercalating microcellulose fibers into graphene oxide (GO) nanosheets, followed by high-temperature carbonization. The abundant porous...
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Article
Liquid-phase hydrogenation of dimethyl maleate to 1,4-butanediol over a sorbitol-modified Cu@C/ZnO catalyst
With the growing global demand for biodegradable plastics, the hydrogenation of dimethyl maleate (DMM) to produce 1,4-butanediol (BDO), raw materials for poly(butylene succinate), has become one of the hot spo...
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Article
Relationship between changes in late-life blood pressure and the risk of frailty and mortality among older population in China: a cohort study based on CLHLS
The evidence regarding the effects of blood pressure changes on older individuals remains inconclusive, and the impact of frailty throughout the life course is not known. We investigated the associations of di...
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Article
The resistance to short-term dehydration in the bdelloid rotifer Rotaria rotatoria from different climate regions
Exceptional resistance to dehydration allows species of bdelloid rotifers to tolerate desiccation stress in unpredictable habitats. The roles of exogenous and endogenous factors in resistance to short-term deh...
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Article
Legionella effector LnaB is a phosphoryl AMPylase that impairs phosphosignalling
AMPylation is a post-translational modification in which AMP is added to the amino acid side chains of proteins1,2. Here we show that, with ATP as the ligand and actin as the host activator, the effector protein ...
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Improvement of impact properties of Al–Si–Mg alloy via solution treatment and joint modification with Sr and La
An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented, where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly employed. The samples were sol...