220 Result(s)

Article

Integrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population

Alternative polyadenylation (APA) plays a crucial role in cancer biology. Here, we used data from the 3′aQTL-atlas, GTEx, and the China Nan**g Lung Cancer GWAS database to explore the association between apaQ...

Huiwen Xu, Yutong Wu, Qiong Chen, Yuhui Yu, Qianyao Meng, Na Qin… in Communications Biology (2024)

Article

Characterization of air pollution and associated health risks in Gansu Province, China from 2015 to 2022

Air pollution poses a major threat to both the environment and public health. The air quality index (AQI), aggregate AQI, new health risk–based air quality index (NHAQI), and NHAQI-WHO were employed to quantit...

Bowen Cheng, Yuxia Ma, Pengpeng Qin, Wanci Wang, Yuhan Zhao… in Scientific Reports (2024)

Article

Adoption of the cardiopulmonary exercise test in the exercise ability and cardiopulmonary function rehabilitation of coronary artery disease (CAD) patients

This study aimed to explore the application of cardiopulmonary exercise testing in coronary artery disease (CAD) patients, evaluate its impact on exercise ability and cardiopulmonary function in patients with ...

Lingling Wang, Fan Mei, Mengyi Min, **uyan He, Lili Luo… in BMC Cardiovascular Disorders (2024)

Article

Construction and application of procedural pathways combined with information management in nursing staff skills training system

To explore the application effect of procedural pathways combined with information management in the construction of nursing staff skills training system.

Li** Cui, Yuting Dong, Shan Zhang, Wenxia Ma, Min Li in BMC Medical Education (2024)

Article

USP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer

This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns...

Qian-Lan Wang, Shun-Yuan Lu, Dan-Dan Xu, **-**a Ma… in Cancer Immunology, Immunotherapy (2024)

Article

Genomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer

Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the “Fudan University Shanghai C...

Ruo Qi Li, Lei Yan, Ling Zhang, Hai **a Ma, Hui Wen Wang, Peng Bu… in Scientific Reports (2024)

Article

Integrated analysis of the DNA methylome and RNA transcriptome during the development of skeletal muscle in Duroc pigs

Skeletal muscle development plays a crucial role in yield and quality of pork; however, this process is influenced by various factors. In this study, we employed whole-genome bisulfite sequencing (WGBS) and tr...

Shi-yin Li, Yun-zhou Wang, Wei Chen, Li-xia Ma, Jian-min Zhang… in BMC Genomics (2024)

Article

Evaluating the mosquito vector range for two orthobunyaviruses: Oya virus and Ebinur Lake virus

Mosquito-borne viruses cause various infectious diseases in humans and animals. Oya virus (OYAV) and Ebinur Lake virus (EBIV), belonging to the genus Orthobunyavirus within the family Peribunyaviridae, are recogn...

Siyuan Liu, **aoyu Wang, Fei Wang, Wahid Zaman, Cihan Yang… in Parasites & Vectors (2024)

Article

Perceptions of Chinese women with a history of gestational diabetes regarding health behaviors and related factors: a directed qualitative content analysis

Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy and is associated with adverse outcomes in both mothers and their children. After delivery, women who experien...

**aoxia Ma, Yun Yang, Shuhua Qian, Yan Ding, Qi** Lin, Na Wang in BMC Public Health (2024)

Article

Inter- and trans-generational impacts of real-world PM_2.5 exposure on male-specific primary hypogonadism

Exposure to PM_2.5, a harmful type of air pollution, has been associated with compromised male reproductive health; however, it remains unclear whether such exposure can elicit transgenerational effects on male fe...

**aoyu Wei, Zhonghao Zhang, Yayun Gu, Rong Zhang, Jie Huang, Feng Li… in Cell Discovery (2024)

Article

Correction: The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth

**g Qian, Yanxia Ma, William M. Tahaney, Cassandra L. Moyer… in Breast Cancer Research (2024)

Article

Investigating the causal relationship between immune cell and Alzheimer’s disease: a mendelian randomization analysis

Complex interactions between the immune system and the brain may affect neural development, survival, and function, with etiological and therapeutic implications for neurodegenerative diseases. However, previo...

Min Shen, Linlin Zhang, Chen Chen, **aocen Wei, Yuning Ma, Yuxia Ma in BMC Neurology (2024)

Article

Potential causal associations between leisure sedentary behaviors, physical activity, sleep traits, and myopia: a Mendelian randomization study

Myopia is the most prevalent refractive error and a growing global health concern that significantly affects visual function. Researchers have recently emphasized considerably on the influence of lifestyle on ...

**ao-Bin Zhang, He-He Jiang, Lin-Lin Zhang, Chun-**g Li, Chen Chen… in BMC Ophthalmology (2024)

Article

Characterization of intestinal fungal community diversity in people living with HIV/AIDS (PLWHA)

Acquired Immune Deficiency Syndrome (AIDS) is a highly dangerous infectious disease caused by the Human Immunodeficiency Virus (HIV), a virus that attacks the human immune system. To explore the correlation be...

Pengfei Meng, Guichun Zhang, **uxia Ma, Xue Ding, **yuan Song… in AIDS Research and Therapy (2024)

Article

Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease

Tubulointerstitial fibrosis plays an important role in the progression of diabetic kidney disease (DKD). Sacubitril/valsartan (Sac/Val) exerts a robust beneficial effect in DKD. However, the potential function...

**ng-Jian Zhang, Cong-Cong Liu, Zuo-Lin Li, Lin Ding… in Diabetology & Metabolic Syndrome (2024)

Article

The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth

The most aggressive form of breast cancer is triple-negative breast cancer (TNBC), which lacks expression of the estrogen receptor (ER) and progesterone receptor (PR), and does not have overexpression of the h...

**g Qian, Yanxia Ma, William M. Tahaney, Cassandra L. Moyer… in Breast Cancer Research (2024)

Article

Full quantitative resource utilization of raw mustard waste through integrating a comprehensive approach for producing hydrogen and soil amendments

Pickled mustard, the largest cultivated vegetable in China, generates substantial waste annually, leading to significant environmental pollution due to challenges in timely disposal, leading to decomposition a...

Ling Zhou, JiaZhen Sun, **aoJun Xu, Ming**a Ma, YongZhi Li… in Microbial Cell Factories (2024)

Article

Gasdermin E dictates inflammatory responses by controlling the mode of neutrophil death

Both lytic and apoptotic cell death remove senescent and damaged cells in living organisms. However, they elicit contrasting pro- and anti-inflammatory responses, respectively. The precise cellular mechanism t...

Fengxia Ma, Laxman Ghimire, Qian Ren, Yu** Fan, Tong Chen… in Nature Communications (2024)

Article

How to tackle non-specific low back pain among adult patients? A systematic review with a meta-analysis to compare four interventions

To tackle non-specific low back pain (NSLBP) among patients and find the most effective solution and to quantitatively synthesize the overall effect of motor control training (MCT) compared with Pilates, McKen...

Yawen Jiang, Ya** Xu, **angrui Kong… in Journal of Orthopaedic Surgery and Research (2024)

Article

Green electrosynthesis of 3,3’-diamino-4,4’-azofurazan energetic materials coupled with energy-efficient hydrogen production over Pt-based catalysts

The broad employment of clean hydrogen through water electrolysis is restricted by large voltage requirement and energy consumption because of the sluggish anodic oxygen evolution reaction. Here we demonstrate...

Jiachen Li, Yuqiang Ma, Cong Zhang, Chi Zhang, Huijun Ma… in Nature Communications (2023)